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Ephrin B2蛋白重組兔單克隆抗體

產品貨號：

BN42153R
中文名稱：

Ephrin B2蛋白重組兔單克隆抗體
英文名稱：

Rabbit anti-Ephrin B2 Monoclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN42153R-50ul

50ul

￥2020.00

交叉反應：Human,Rat(predicted:Mouse) 推薦應用：WB,IHC-P,IF
BN42153R-100ul

100ul

￥3240.00

交叉反應：Human,Rat(predicted:Mouse) 推薦應用：WB,IHC-P,IF

產品描述

英文名稱	Ephrin B2
中文名稱	Ephrin B2蛋白重組兔單克隆抗體
別名	EFN B2; EFNB 2; Efnb2; EFNB2_HUMAN; Eph related receptor tyrosine kinase ligand 5; EPH-related receptor tyrosine kinase ligand 5; ephrin B2; Ephrin-B2; EphrinB2; EPLG 5; EPLG5; Htk L; HTK ligand; HTK-L; HTKL; LERK 5; LERK-5; LERK5; Ligand of eph related kinase 5; MGC126226; MGC126227; MGC126228; OTTMUSP00000024973.
研究領域	細胞生物神經生物學信號轉導激酶和磷酸酶
抗體來源	Rabbit
克隆類型	Monoclonal
克隆號	3A7
交叉反應	Human, Rat, (predicted: Mouse, )
產品應用	WB=1:500-1000 IHC-P=1:400-800 ICC=1:50-200 IF=1:50-200 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	34kDa
細胞定位	細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human Ephrin B2:
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008] Function: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons. Subcellular Location: Membrane. Tissue Specificity: Lung and kidney. Post-translational modifications: Inducible phosphorylation of tyrosine residues in the cytoplasmic domain. Similarity: Belongs to the ephrin family. Contains 1 ephrin RBD (ephrin receptor-binding) domain. SWISS: P52799 Gene ID: 1948 Database links: Entrez Gene: 1948 Human Entrez Gene: 13642 Mouse Omim: 600527 Human SwissProt: P52799 Human SwissProt: P52800 Mouse Unigene: 149239 Human Unigene: 209813 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.