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細胞角蛋白19重組兔單克隆抗體

產品貨號：

BN42076R
中文名稱：

細胞角蛋白19重組兔單克隆抗體
英文名稱：

Rabbit anti-Cytokeratin 19 Monoclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN42076R-50ul

50ul

￥2020.00

交叉反應：Human(predicted:Mouse) 推薦應用：WB,IHC-P,IHC-F,ICC,IF
BN42076R-100ul

100ul

￥3240.00

交叉反應：Human(predicted:Mouse) 推薦應用：WB,IHC-P,IHC-F,ICC,IF

產品描述

英文名稱	Cytokeratin 19
中文名稱	細胞角蛋白19重組兔單克隆抗體
別名	40 kDa keratin intermediate filament; CK 19; ck19; CK19; CK-19; KRT19; Cytokeratin19; Cytokeratin-19; k19; k1cs; Keratin 19; Keratin-19; Keratin type I 40 kD; Keratin type i 40kD; Keratin type I cytoskeletal 19; krt19; mgc15366; K1C19_HUMAN; Keratin, type I cytoskeletal 19; Keratin, type I, 40 kd
研究領域	腫瘤細胞生物干細胞
抗體來源	Rabbit
克隆類型	Monoclonal
克隆號	2F3
交叉反應	Human, (predicted: Mouse, )
產品應用	WB=1:2000-5000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:20-100 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	44kDa
細胞定位	細胞漿細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	Recombinant human Cytokeratin 19 protein, around C-terminal 100aa.:
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008] Function: Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. Subunit: Heterotetramer of two type I and two type II keratins. Interacts with PNN and the actin-binding domain of DMD. Interacts with HCV core protein. Tissue Specificity: Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin. Similarity: Belongs to the intermediate filament family. SWISS: P08727 Gene ID: 3880 Database links: Entrez Gene: 3880 Human Entrez Gene: 16669 Mouse Omim: 148020 Human SwissProt: P08727 Human SwissProt: P19001 Mouse Unigene: 654568 Human Unigene: 439699 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.