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    轉鐵蛋白單克隆抗體
    • 產品貨號:
      BN41978M
    • 中文名稱:
      轉鐵蛋白單克隆抗體
    • 英文名稱:
      Mouse anti-Transferrin(1F10) Monoclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41978M-50ul

      50ul

      ¥1486.00

      交叉反應:Human 推薦應用:WB,ELISA

    • BN41978M-100ul

      100ul

      ¥2360.00

      交叉反應:Human 推薦應用:WB,ELISA

    產品描述

    英文名稱Transferrin(1F10)
    中文名稱轉鐵蛋白單克隆抗體
    別    名Apotransferrin; Beta 1 metal binding globulin; DKFZp781D0156; PRO1400; PRO1557; PRO2086; Serotransferrin precursor; Siderophilin; TF; Transferin; Transferrin.  
    研究領域腫瘤  細胞生物  免疫學  轉錄調節因子  
    抗體來源Mouse
    克隆類型Monoclonal
    克 隆 號1F10
    交叉反應Human, 
    產品應用WB=1:500-2000 ELISA=1:5000-10000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量77kDa
    細胞定位分泌型蛋白 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原Full length native Transferrin protein purified from human plasma: 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009].

    Function:
    Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

    Subunit:
    Monomer.

    Subcellular Location:
    Secreted.

    Tissue Specificity:
    Expressed by the liver and secreted in plasma.

    DISEASE:
    Defects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.

    Similarity:
    Belongs to the transferrin family.
    Contains 2 transferrin-like domains.

    SWISS:
    P02787

    Gene ID:
    7018

    Database links:

    Entrez Gene: 7018 Human

    Entrez Gene: 22041 Mouse

    Entrez Gene: 24825 Rat

    Omim: 190000 Human

    SwissProt: P02787 Human

    SwissProt: Q921I1 Mouse

    SwissProt: P12346 Rat

    Unigene: 518267 Human

    Unigene: 37214 Mouse

    Unigene: 91296 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
















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