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    蛋白偶聯受體55抗體
    • 產品貨號:
      BN41963R
    • 中文名稱:
      蛋白偶聯受體55抗體
    • 英文名稱:
      Rabbit anti-GPR55 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41963R-50ul

      50ul

      ¥1486.00

      交叉反應:Human,Mouse,Rat(predicted:Chicken,Dog,Horse,Rabbit) 推薦應用:WB,IHC-P,Flow-Cyt,ELISA

    • BN41963R-100ul

      100ul

      ¥2360.00

      交叉反應:Human,Mouse,Rat(predicted:Chicken,Dog,Horse,Rabbit) 推薦應用:WB,IHC-P,Flow-Cyt,ELISA

    • BN41963R-200ul

      200ul

      ¥3490.00

      交叉反應:Human,Mouse,Rat(predicted:Chicken,Dog,Horse,Rabbit) 推薦應用:WB,IHC-P,Flow-Cyt,ELISA

    產品描述

    英文名稱GPR55
    中文名稱蛋白偶聯受體55抗體
    別    名GPCR GPR55; G protein coupled receptor 55; G protein-coupled receptor 55; G protein-coupled receptor 55; GPCR GPR55; GPR 55; GPR55; Probable G protein coupled receptor 55; GPR55_HUMAN.  
    研究領域心血管  細胞生物  信號轉導  G蛋白偶聯受體  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human,  (predicted: Chicken, Dog, Horse, Rabbit, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=2ug/Test 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量37kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human GPR55:141-240/319 <Extracellular>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR55 is a member of this family (subfamily Orphan-A). It has been reported to be expressed in the brain, where mRNA transcripts were detected in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain. ESTs have been isolated from liver/spleen libraries.

    Function:
    May be involved in hyperalgesia associated with inflammatory and neuropathic pain. Receptor for L-alpha-lysophosphatidylinositol (LPI). LPI induces Ca(2+) release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. Putative cannabinoid receptor. May play a role in bone physiology by regulating osteoclast number and function.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein.

    Tissue Specificity:
    Expressed in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain or in the liver. Expressed in osteoclasts and osteoblasts.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family.

    SWISS:
    Q9Y2T6

    Gene ID:
    9290

    Database links:

    Entrez Gene: 9290 Human

    Omim: 604107 Human

    SwissProt: Q9Y2T6 Human

    Unigene: 114545 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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