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    細胞表面趨化因子受體5抗體
    • 產品貨號:
      BN41868R
    • 中文名稱:
      細胞表面趨化因子受體5抗體
    • 英文名稱:
      Rabbit anti-CXCR5 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41868R-50ul

      50ul

      ¥1486.00

      交叉反應:Human(predicted:Mouse,Rat,Pig,Cow,Rabbit) 推薦應用:WB,ELISA

    • BN41868R-100ul

      100ul

      ¥2360.00

      交叉反應:Human(predicted:Mouse,Rat,Pig,Cow,Rabbit) 推薦應用:WB,ELISA

    • BN41868R-200ul

      200ul

      ¥3490.00

      交叉反應:Human(predicted:Mouse,Rat,Pig,Cow,Rabbit) 推薦應用:WB,ELISA

    產品描述

    英文名稱CXCR5
    中文名稱細胞表面趨化因子受體5抗體
    別    名BLR 1; BLR1; Burkitt lymphoma receptor 1; Burkitt lymphoma receptor 1 GTP binding protein; C X C chemokine receptor type 5; C-X-C chemokine receptor type 5; CD 185; CD185; CD185 antigen; Chemokine C X C motif receptor 5; Chemokine CXC motif receptor 5; Chemokine receptor 5; CXC chemokine receptor type 5; CXC R5; CXC-R5; CXCR 5; CXCR-5; Cxcr5; CXCR5_HUMAN; MDR 15; MDR-15; MDR15; MGC117347; Monocyte derived receptor 15; Monocyte-derived receptor 15.  



    研究領域腫瘤  細胞生物  免疫學  信號轉導  趨化因子  G蛋白偶聯受體  b-淋巴細胞  G蛋白信號  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human,  (predicted: Mouse, Rat, Pig, Cow, Rabbit, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量45kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human CXCR5/CD185:281-372/372 <Cytoplasmic>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹The CXCR5 gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. CXCR5 protein is predicted to be a seven transmembrane G protein coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of the gene and its mouse conterpart strongly suggest the essential function of the protein is in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen.

    Function:
    Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein.

    Tissue Specificity:
    Expression in mature B-cells and Burkitt lymphoma cells.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family.

    SWISS:
    P32302

    Gene ID:
    643

    Database links:

    Entrez Gene: 643 Human

    Entrez Gene: 12145 Mouse

    Entrez Gene: 29363 Rat

    Omim: 601613 Human

    SwissProt: P32302 Human

    SwissProt: Q04683 Mouse

    SwissProt: P34997 Rat

    Unigene: 113916 Human

    Unigene: 490637 Mouse

    Unigene: 6246 Mouse

    Unigene: 120732 Rat

    Unigene: 127121 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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