最近搜索:細(xì)胞培養(yǎng) 微生物學(xué) 分子生物 生物化學(xué)
    首頁>>免疫學(xué)>>一抗>>離子鈣接頭蛋白抗體
    離子鈣接頭蛋白抗體
    • 產(chǎn)品貨號(hào):
      BN41859R
    • 中文名稱:
      離子鈣接頭蛋白抗體
    • 英文名稱:
      Rabbit anti-AIF1/Iba1 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號(hào)

      產(chǎn)品規(guī)格

      售價(jià)

      備注

    • BN41859R-50ul

      50ul

      ¥1486.00

      交叉反應(yīng):Human 推薦應(yīng)用:WB,IHC-P,ELISA

    • BN41859R-100ul

      100ul

      ¥2360.00

      交叉反應(yīng):Human 推薦應(yīng)用:WB,IHC-P,ELISA

    產(chǎn)品描述

    英文名稱AIF1/Iba1
    中文名稱離子鈣接頭蛋白抗體
    別    名AIF 1; AIF1; AIF1 protein; IBa1; iba-1; IBa 1; allograft inflammatory factor 1; Allograft inflammatory factor 1 splice variant G; balloon angioplasty responsive transcription; BART 1; G1; G1 putative splice variant of allograft inflamatory factor 1; IBA 1; IBA1; interferon gamma responsive transcript; Ionized calcium binding adapter molecule 1; ionized calcium-binding adapter molecule; IRT 1; IRT1; Microglia response factor; MRF1; Protein G1.  
    研究領(lǐng)域細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human, 
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:50-100 (石蠟切片需做抗原修復(fù))
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量16.7kDa
    細(xì)胞定位細(xì)胞漿 細(xì)胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human AIF1:6-36/147 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M PBS(pH7.4) with 0.03% Proclin300.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹Allograft Inflammatory Factor-1 (AIF1)or ionized calcium-binding adaptor molecule 1 (Iba1) is expressed selectively in microglia/macrophages and is a Ca2+-binding peptide produced by activated monocytes and microglial cells. It has been suggested that AIF1 expression is associated with chronic inflammatory processes. AIF1 is expressed by activated monocytes and might participate in a variety of pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts.

    Function:
    Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

    Subunit:
    Homodimer (Potential). Monomer. Interacts with LCP1.

    Subcellular Location:
    Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.

    Tissue Specificity:
    Detected in T-lymphocytes and peripheral blood mononuclear cells.

    Similarity:
    Contains 2 EF-hand domains.

    SWISS:
    P55008

    Gene ID:
    199

    Database links:

    Entrez Gene: 199 Human

    Entrez Gene: 11629 Mouse

    Entrez Gene: 29427 Rat

    Omim: 601833 Human

    SwissProt: P55008 Human

    SwissProt: O70200 Mouse

    SwissProt: P55009 Rat

    Unigene: 76364 Human

    Unigene: 10747 Mouse

    Unigene: 32080 Rat 



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    離子鈣接頭蛋白主要在小膠質(zhì)細(xì)胞表達(dá).


    亚洲AV午夜成人影院老师机影院| 激情97综合亚洲色婷婷五| 亚洲成色在线综合网站| 亚洲伊人久久成综合人影院| 亚洲AV无码之日韩精品| 五月天婷亚洲天综合网精品偷| 亚洲AV综合色区无码一二三区| 亚洲成aⅴ人片久青草影院按摩| 亚洲乱妇老熟女爽到高潮的片 | 亚洲国产综合AV在线观看| 亚洲日本在线电影| 亚洲av无码一区二区三区天堂| 亚洲av无码专区亚洲av不卡| 亚洲av永久无码| 亚洲不卡AV影片在线播放| 亚洲日韩VA无码中文字幕 | 亚洲区日韩区无码区| 国产亚洲日韩在线三区| 亚洲欧洲美洲无码精品VA| 亚洲大尺度无码专区尤物| 亚洲最大的成网4438| 亚洲沟沟美女亚洲沟沟| 亚洲免费在线观看视频| 亚洲国产精品免费观看| 久久亚洲AV成人无码国产最大| 亚洲成人影院在线观看| 77777亚洲午夜久久多人| 久久精品国产亚洲网站| 亚洲天堂视频在线观看| 亚洲国产成人久久| 亚洲无码一区二区三区| 午夜亚洲乱码伦小说区69堂| 亚洲中文字幕成人在线| 亚洲AV永久无码精品一百度影院| 亚洲日本精品一区二区| 99999久久久久久亚洲| www亚洲精品久久久乳| 中文字幕第一页亚洲| 亚洲国产精品va在线播放| 亚洲美女视频一区| 亚洲日韩精品国产3区|