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BN41686R-50ul
50ul
￥1486.00
交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse) 推薦應(yīng)用：WB,IHC-P,ELISA
BN41686R-100ul
100ul
￥2360.00
交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse) 推薦應(yīng)用：WB,IHC-P,ELISA
BN41686R-200ul
200ul
￥3490.00
交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse) 推薦應(yīng)用：WB,IHC-P,ELISA
產(chǎn)品描述
| 英文名稱 | Oxytocin R |
| 中文名稱 | 催產(chǎn)素受體(縮宮素受體)抗體 |
| 別 名 | Oxytocin R; OT R; OT-R; OTR 1; OTR; OTR1; OXT R; OXTR; Oxytocin receptor; OXYR_HUMAN. |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 生長(zhǎng)因子和激素 細(xì)胞膜受體 內(nèi)分泌病 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, Rat, (predicted: Dog, Pig, Cow, Horse, ) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 43kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse oxytocin receptor:325-388/388 <Cytoplasmic> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. Oxytocin receptor has been reported in breast, central nervous system, heart, ovary, placenta, prostate, salivary gland, testis, uterus, and vessel. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. SWISS: P97926 Gene ID: 18430 Database links: Entrez Gene: 5021 Human Entrez Gene: 18430 Mouse Omim: 167055 Human SwissProt: P30559 Human SwissProt: P97926 Mouse SwissProt: Q28756 Sheep Unigene: 2820 Human Unigene: 333310 Mouse Unigene: 6841 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. OTR在人的子宮平滑肌細(xì)胞膜上有縮宮素受體，縮宮素引起子宮收縮的機(jī)制可能是通過(guò)激活縮宮素受體而實(shí)現(xiàn)的。經(jīng)研究發(fā)現(xiàn)，縮宮素受體在外周組織和中樞神經(jīng)系統(tǒng)內(nèi)均有分布。縮宮素與不同組織、細(xì)胞上的縮宮素受體結(jié)合，通過(guò)多種信號(hào)轉(zhuǎn)導(dǎo)途徑而發(fā)揮作用。 |
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