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    骨形態發生蛋白2抗體
    • 產品貨號:
      BN41646R
    • 中文名稱:
      骨形態發生蛋白2抗體
    • 英文名稱:
      Rabbit anti-BMP2 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41646R-50ul

      50ul

      ¥1486.00

      交叉反應:Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,GuineaPig) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN41646R-100ul

      100ul

      ¥2360.00

      交叉反應:Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,GuineaPig) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN41646R-200ul

      200ul

      ¥3490.00

      交叉反應:Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,GuineaPig) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    產品描述

    英文名稱BMP2
    中文名稱骨形態發生蛋白2抗體
    別    名Bone morphogenetic protein 2; BMP 2; BMP 2A; BMP2A; BMP-2; BMP2_HUMAN.  
    研究領域細胞生物  免疫學  發育生物學  神經生物學  生長因子和激素  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Guinea Pig, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量13/44kDa
    細胞定位分泌型蛋白 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human BMP2:341-396/396 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.

    Function:
    Induces cartilage and bone formation.

    Subunit:
    Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with GREM2, RGMA, RGMB and RGMC. Interacts with ASPN.

    Subcellular Location:
    Secreted.

    Tissue Specificity:
    Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.

    Similarity:
    Belongs to the TGF-beta family.

    SWISS:
    P12643

    Gene ID:
    650

    Database links:

    Entrez Gene: 650 Human

    Entrez Gene: 12156 Mouse

    Entrez Gene: 29373 Rat

    Omim: 112261 Human

    SwissProt: P12643 Human

    SwissProt: P21274 Mouse

    SwissProt: P49001 Rat

    Unigene: 73853 Human

    Unigene: 103205 Mouse

    Unigene: 90931 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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