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    脊髓灰質炎病毒受體相關蛋白4抗體
    • 產品貨號:
      BN41609R
    • 中文名稱:
      脊髓灰質炎病毒受體相關蛋白4抗體
    • 英文名稱:
      Rabbit anti-Nectin 4 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41609R-50ul

      50ul

      ¥1486.00

      交叉反應:Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Rat) 推薦應用:WB,ELISA

    • BN41609R-100ul

      100ul

      ¥2360.00

      交叉反應:Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Rat) 推薦應用:WB,ELISA

    • BN41609R-200ul

      200ul

      ¥3490.00

      交叉反應:Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Rat) 推薦應用:WB,ELISA

    產品描述

    英文名稱Nectin 4
    中文名稱脊髓灰質炎病毒受體相關蛋白4抗體
    別    名Ig superfamily receptor LNIR; Nectin 4; poliovirus receptor-related 4; PRR4; poliovirus receptor related 4; DKFZp686K05193; EDSS1; Nectin-4; poliovirus receptor-related 4; Processed poliovirus receptor-related protein 4; pvrl4; PVRL4_HUMAN.  
    研究領域腫瘤  細胞生物  免疫學  細菌及病毒  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse,  (predicted: Rat, Pig, Cow, Horse, Rabbit, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量53kDa
    細胞定位細胞膜 分泌型蛋白 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Nectin 4:151-250/510 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

    Function:
    Self-associates. Interacts via its Ig-like V-type domain with PVRL1/nectin-1 Ig-like V-type domain. Interacts via its C-terminus with MLLT4. Binds to Measles virus protein H and acts as a receptor for this virus.

    Subcellular Location:
    Cell membrane; Single-pass type I membrane protein (Potential). Cell junction, adherens junction. Processed poliovirus receptor-related protein 4: Secreted.

    Tissue Specificity:
    Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma.

    Similarity:
    Belongs to the nectin family.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    SWISS:
    Q96NY8

    Gene ID:
    81607

    Database links:

    Entrez Gene: 81607 Human

    Entrez Gene: 71740 Mouse

    Entrez Gene: 498281 Rat

    Omim: 609607 Human

    SwissProt: Q5E9Z9 Cow

    SwissProt: Q96NY8 Human

    SwissProt: Q8R007 Mouse

    Unigene: 492490 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.














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