最近搜索:細(xì)胞培養(yǎng) 微生物學(xué) 分子生物 生物化學(xué)
    首頁>>免疫學(xué)>>一抗>>波形蛋白抗體
    波形蛋白抗體
    • 產(chǎn)品貨號:
      BN41586R
    • 中文名稱:
      波形蛋白抗體
    • 英文名稱:
      Rabbit anti-Vimentin Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產(chǎn)品規(guī)格

      售價(jià)

      備注

    • BN41586R-50ul

      50ul

      ¥1486.00

      交叉反應(yīng):Human,Mouse,Rat(predicted:Chicken,Pig,Cow,Goat) 推薦應(yīng)用:WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

    • BN41586R-100ul

      100ul

      ¥2360.00

      交叉反應(yīng):Human,Mouse,Rat(predicted:Chicken,Pig,Cow,Goat) 推薦應(yīng)用:WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

    • BN41586R-200ul

      200ul

      ¥3490.00

      交叉反應(yīng):Human,Mouse,Rat(predicted:Chicken,Pig,Cow,Goat) 推薦應(yīng)用:WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

    產(chǎn)品描述

    英文名稱Vimentin
    中文名稱波形蛋白抗體
    別    名FLJ36605; OTTHUMP00000019224; VIM; VIME_HUMAN; Vimentin.  
    研究領(lǐng)域腫瘤  細(xì)胞生物  免疫學(xué)  發(fā)育生物學(xué)  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  干細(xì)胞  細(xì)胞骨架  腫瘤細(xì)胞生物標(biāo)志物  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human, Mouse,  (predicted: Rat, Chicken, Pig, Cow, Goat, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量53kDa
    細(xì)胞定位細(xì)胞漿 細(xì)胞外基質(zhì) 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Vimentin:371-466/466 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009]

    Function:
    Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.
    Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.

    Subunit:
    Homopolymer assembled from elementary dimers. Interacts with HCV core protein. Interacts with LGSN and SYNM. Interacts (via rod region) with PLEC (via CH 1 domain) (By similarity). Interacts with SLC6A4. Interacts with STK33. Interacts with LARP6. Interacts with RAB8B (By similarity).

    Subcellular Location:
    Cytoplasm.

    Tissue Specificity:
    Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.

    Post-translational modifications:
    Filament disassembly during mitosis is promoted by phosphorylation at Ser-55 as well as by nestin (By similarity). One of the most prominent phosphoproteins in various cells of mesenchymal origin. Phosphorylation is enhanced during cell division, at which time vimentin filaments are significantly reorganized. Phosphorylation by PKN1 inhibits the formation of filaments. Phosphorylated at Ser-56 by CDK5 during neutrophil secretion in the cytoplasm. Phosphorylated by STK33.

    Similarity:
    Belongs to the intermediate filament family.

    SWISS:
    P08670

    Gene ID:
    7431

    Database links:

    Entrez Gene: 7431 Human

    Entrez Gene: 22352 Mouse

    Entrez Gene: 81818 Rat

    Omim: 193060 Human

    SwissProt: P08670 Human

    SwissProt: P20152 Mouse

    SwissProt: P31000 Rat

    Unigene: 455493 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    Vimentin—波形蛋白。是五種主要的中間絲之一,存在于各種正常和病理性間質(zhì)來源的組織,如纖維母細(xì)胞、內(nèi)皮細(xì)胞、淋巴細(xì)胞等正常細(xì)胞和肉瘤、淋巴瘤、黑色素瘤等腫瘤。波形蛋白是負(fù)責(zé)維持細(xì)胞骨架完整性的蛋白之一。


    日韩国产精品亚洲а∨天堂免| 亚洲国产成人99精品激情在线| 亚洲AV无码国产精品色午友在线 | www.亚洲成在线| 精品亚洲aⅴ在线观看| 亚洲va久久久噜噜噜久久狠狠| 亚洲无线码在线一区观看| 亚洲国产精品一区二区三区久久 | 亚洲AV永久无码精品一区二区国产 | 亚洲日韩在线中文字幕第一页| 国产精品亚洲二区在线| 亚洲国产成人AV网站| 婷婷亚洲综合一区二区| 在线观看亚洲网站| 亚洲AV永久无码精品一区二区国产 | 亚洲一级毛片免观看| 亚洲中文字幕人成乱码| 亚洲第一页在线播放| 亚洲视频一区二区在线观看| 久久亚洲AV成人无码软件| 亚洲综合男人的天堂色婷婷| 亚洲黄色网站视频| 亚洲欧洲日产v特级毛片| 亚洲国产精品张柏芝在线观看| 亚洲婷婷天堂在线综合| 亚洲AV无码专区在线亚| 中文字幕精品三区无码亚洲| 亚洲另类自拍丝袜第五页| 亚洲av永久中文无码精品综合| 在线精品自拍亚洲第一区| 亚洲精品无码激情AV| 亚洲永久精品ww47| 国产亚洲av片在线观看16女人| 亚洲av无码潮喷在线观看| 亚洲酒色1314狠狠做| 亚洲色欲色欲www| 亚洲AV无码AV男人的天堂不卡 | 蜜芽亚洲av无码精品色午夜| 亚洲一卡2卡3卡4卡国产网站| 亚洲色欲色欲www| 在线精品自拍亚洲第一区|