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    外周髓磷脂P0蛋白/P0蛋白抗體
    • 產品貨號:
      BN41528R
    • 中文名稱:
      外周髓磷脂P0蛋白/P0蛋白抗體
    • 英文名稱:
      Rabbit anti-Myelin Protein Zero Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41528R-50ul

      50ul

      ¥1486.00

      交叉反應:Dog,Rat,Mouse(predicted:GuineaPig,Rabbit,Horse,Cow,Pig,Human) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN41528R-100ul

      100ul

      ¥2360.00

      交叉反應:Dog,Rat,Mouse(predicted:GuineaPig,Rabbit,Horse,Cow,Pig,Human) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN41528R-200ul

      200ul

      ¥3490.00

      交叉反應:Dog,Rat,Mouse(predicted:GuineaPig,Rabbit,Horse,Cow,Pig,Human) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    產品描述

    英文名稱Myelin Protein Zero
    中文名稱外周髓磷脂P0蛋白/P0蛋白抗體
    別    名peripheral myelin prothein Zero; MPZ; MPP; Myelin P0 protein; CHM; CMT1; CMT1B; DSS; MYELIN GLYCOPROTEIN P-ZERO; MYELIN PROTEIN PERIPHERAL; Myelin protein zero; P0; MYP0_HUMAN.   


    研究領域神經生物學  信號轉導  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Mouse, Rat, Dog,  (predicted: Human, Pig, Cow, Horse, Rabbit, Guinea Pig, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量24kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human P0 protein:175-248/248 <Cytoplasmic>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Myelin protein-zero is the major structural protein of peripheral myelin, accounting for more than 50% of the protein present in the sheath of peripheral nerves. Expression of the gene encoding Myelin protein-zero (MPZ) is restricted to Schwann cells; MPZ is not found in the CNS. An integral membrane glycoprotein of ~28kDa, Myelin protein-zero is thought to link adjacent lamellae and thereby stabilize the myelin assembly. The other 3 major components of myelin are myelin basic protein, myelin proteolipid protein and myelin-associated glycoprotein.

    Subunit:
    Homodimer and homotetramer.

    Subcellular Location:
    Cell membrane; Single-pass type I membrane protein.

    Tissue Specificity:
    Found only in peripheral nervous system Schwann cells.

    Similarity:
    Belongs to the myelin P0 protein family.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    SWISS:
    P25189

    Gene ID:
    4359

    Database links:

    Entrez Gene: 4359 Human

    Entrez Gene: 17528 Mouse

    Omim: 159440 Human

    SwissProt: P25189 Human

    SwissProt: P27573 Mouse

     Unigene: 591486 Human

    Unigene: 93883 Human

    Unigene: 9986 Mouse

     UniProtKB/Swiss-Prot: P25189.1




    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    成熟的周圍神經系統髓鞘主要的蛋白為P0蛋白,分子量28KDa,它具有單個跨膜區,是IgG超家族的成員之一。













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