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脂肪細(xì)胞增強(qiáng)結(jié)合蛋白1

產(chǎn)品貨號：

BN41527R
中文名稱：

脂肪細(xì)胞增強(qiáng)結(jié)合蛋白1
英文名稱：

Rabbit anti-AEBP1 Polyclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規(guī)格

售價

備注
BN41527R-50ul

50ul

￥1486.00

交叉反應(yīng)：Rat,Mouse,Human 推薦應(yīng)用：IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41527R-100ul

100ul

￥2360.00

交叉反應(yīng)：Rat,Mouse,Human 推薦應(yīng)用：IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41527R-200ul

200ul

￥3490.00

交叉反應(yīng)：Rat,Mouse,Human 推薦應(yīng)用：IHC-P,IHC-F,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱	AEBP1
中文名稱	脂肪細(xì)胞增強(qiáng)結(jié)合蛋白1
別名	AE binding protein 1; ACLP; Adipocyte enhancer binding protein 1; AEBP 1; AEBP1; Aortic carboxypeptidase like protein ACLP;Aortic carboxypeptidase like protein; FLJ33612; AEBP1_HUMAN; Adipocyte enhancer-binding protein 1; AE-binding protein 1; Aortic carboxypeptidase-like protein.
研究領(lǐng)域	免疫學(xué) 染色質(zhì)和核信號轉(zhuǎn)錄調(diào)節(jié)因子結(jié)合蛋白
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Human, (predicted: Mouse, Rat, )
產(chǎn)品應(yīng)用	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	128/80kDa
細(xì)胞定位	細(xì)胞核細(xì)胞漿分泌型蛋白
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human AEBP1:101-200/728
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	This gene encodes a member of carboxypeptidase A protein family. The encoded protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation. Studies in mice suggest that this gene functions in wound healing and abdominal wall development. Overexpression of this gene is associated with glioblastoma. [provided by RefSeq, May 2013]. Function: May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor. Subunit: Interacts with GNG5, NFKBIA, MAPK1, MAPK3 and PTEN. May interact with calmodulin. Binds to DNA in vitro. Subcellular Location: Isoform 1: Secreted. Isoform 2: Cytoplasm (Probable). Nucleus (Probable). Tissue Specificity: Expressed in osteoblast and visceral fat. Post-translational modifications: Phosphorylated by MAPK1 in vitro. Similarity: Belongs to the peptidase M14 family. Contains 1 F5/8 type C domain. SWISS: Q14113 Gene ID: 165 Database links: Entrez Gene: 165 Human Omim: 602981 Human SwissProt: Q14113 Human Unigene: 439463 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.