最近搜索:細胞培養 微生物學 分子生物 生物化學
    首頁>>免疫學>>一抗>>核受體相關因子-1抗體
    核受體相關因子-1抗體
    • 產品貨號:
      BN41503R
    • 中文名稱:
      核受體相關因子-1抗體
    • 英文名稱:
      Rabbit anti-Nurr1 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41503R-50ul

      50ul

      ¥1486.00

      交叉反應:Human,Rat(predicted:Mouse,Pig,Cow,Rabbit) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN41503R-100ul

      100ul

      ¥2360.00

      交叉反應:Human,Rat(predicted:Mouse,Pig,Cow,Rabbit) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN41503R-200ul

      200ul

      ¥3490.00

      交叉反應:Human,Rat(predicted:Mouse,Pig,Cow,Rabbit) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    產品描述

    英文名稱Nurr1
    中文名稱核受體相關因子-1抗體
    別    名Nur-ralated factor 1; Nuclear receptor-related factor 1; Orphan nuclear receptor NR4A2; Orphan nuclear receptor NURR1; Regenerating liver nuclear receptor 1; RNR-1; SL-322; Nuclear orphan receptor HZF-3; T-cell nuclear receptor NOT;HZF 3; HZF3; Immediate-early response protein NOT; Intermediate early receptor protein; NGFI B/nur77 beta type transcription factor homolog; NOT; NR4A2; NR4A2_HUMAN; Nuclear receptor subfamily 4 group A member 2; Nur related protein 1 homolog; Nurr 1;RNR 1; RNR1; TINUR; Transcriptionally inducible nuclear receptor; Transcriptionally inducible nuclear receptor related; Transcriptionally inducible nuclear receptor related 1; Transcriptionally-inducible nuclear receptor.   
    研究領域染色質和核信號  神經生物學  新陳代謝  表觀遺傳學  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Rat,  (predicted: Mouse, Pig, Cow, Rabbit, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量67kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Nurr1:301-400/598 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Nuclear receptor and transcription factor; plays a role in development and maintenance of neurons synthesizing the neurotransmitter dopamine This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full length nature has not been determined.

    Function:
    Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.

    Subunit:
    Interacts with SFPQ, NCOR2, SIN3A and HADC1. The interaction with NCOR2 increases in the absence of PITX3 (By similarity).

    Subcellular Location:
    Nucleus.

    Tissue Specificity:
    Expressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue.

    Similarity:
    Belongs to the nuclear hormone receptor family. NR4 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.

    SWISS:
    P43354

    Gene ID:
    4929

    Database links:

    Entrez Gene: 4929 Human

    Entrez Gene: 18227 Mouse

    Entrez Gene: 54278 Rat

    Omim: 601828 Human

    SwissProt: P43354 Human

    SwissProt: Q06219 Mouse

    SwissProt: Q07917 Rat

    Unigene: 563344 Human

    Unigene: 3507 Mouse

    Unigene: 88129 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    該抗體和類固醇/甲狀腺素受體密切相關的早期應急反應基因,也受各種生長因子的誘導。中腦多巴胺神經細胞和腦干細胞表達。
















    image.png

    image.png

    image.png

    image.png


    亚洲成av人无码亚洲成av人| 亚洲一线产品二线产品| 亚洲AV成人无码网站| 97久久国产亚洲精品超碰热| 亚洲天堂电影在线观看| 亚洲精品一卡2卡3卡三卡四卡| 亚洲图片一区二区| 夜夜亚洲天天久久| 久久精品国产亚洲AV无码偷窥| 亚洲AV无码一区东京热| 亚洲AV日韩AV天堂久久 | 亚洲AV成人无码久久精品老人 | 亚洲成a人片在线观看精品| 亚洲一区二区三区播放在线| 亚洲一区二区三区久久| 亚洲宅男精品一区在线观看| 亚洲日本久久久午夜精品| 亚洲色大成网站www永久网站| 亚洲午夜无码毛片av久久京东热| 亚洲日产乱码一二三区别| 亚洲AV日韩AV永久无码色欲 | 亚洲高清在线视频| 亚洲精品美女在线观看播放| 亚洲国产日韩在线| 亚洲色偷偷综合亚洲av78| 亚洲欧美日韩中文二区| 国产AV无码专区亚洲AV麻豆丫 | 国产亚洲福利精品一区二区| 国产午夜亚洲精品不卡免下载| 亚洲成A∨人片天堂网无码| 国产成人毛片亚洲精品| 国产亚洲一区二区在线观看| 亚洲免费精彩视频在线观看| 亚洲春色另类小说| 亚洲色大情网站www| 亚洲成a人片在线观看国产| 亚洲熟妇无码八AV在线播放| 婷婷亚洲久悠悠色悠在线播放 | 亚洲国产日韩在线观频| 亚洲精品无码成人AAA片| 亚洲无线电影官网|