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胰島素樣生長因子1抗體

產(chǎn)品貨號：

BN41461R
中文名稱：

胰島素樣生長因子1抗體
英文名稱：

Rabbit anti-IGF 1 Polyclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規(guī)格

售價

備注
BN41461R-50ul

50ul

￥1486.00

交叉反應：Dog,Rat,Mouse,Human(predicted:Sheep,Rabbit,Cow,Pig) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA
BN41461R-100ul

100ul

￥2360.00

交叉反應：Dog,Rat,Mouse,Human(predicted:Sheep,Rabbit,Cow,Pig) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA
BN41461R-200ul

200ul

￥3490.00

交叉反應：Dog,Rat,Mouse,Human(predicted:Sheep,Rabbit,Cow,Pig) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱	IGF 1
中文名稱	胰島素樣生長因子1抗體
別名	IBP1; IGF 1; IGF I; IGF-1;IGF IA; IGF IB; IGF1; IGFI; IGFIA; Insulin like growth factor 1 (somatomedin C); Full=Insulin-like growth factor I; Insulin Like Growth Factor 1; Insulin like growth factor IA; Insulin like growth factor IB; Mechano growth factor; MGF; Mechano growth factor; MGF; Somatomedia C; Somatomedin C; IGF1_HUMAN.

研究領域	免疫學發(fā)育生物學信號轉(zhuǎn)導生長因子和激素糖尿病
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse, Rat, Dog, (predicted: Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應用	WB=1:500-2000 ELISA=1:5000-10000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	7.7/21kDa
細胞定位	分泌型蛋白
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human IGF-1:49-100/195
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009] Function: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. Subcellular Location: Secreted. DISEASE: Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. Similarity: Belongs to the insulin family. SWISS: P05019 Gene ID: 3479 Database links: Entrez Gene: 3479 Human Omim: 147440 Human SwissProt: P05019 Human Unigene: 160562 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 胰島素樣生長因子1(IGF-1)是一種生長調(diào)節(jié)激素，由肝分泌并入血液循環(huán)的中性多肽，具有調(diào)節(jié)生長和代謝、胰島素樣及促細胞分裂的活性，主要作用于成人。