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    線粒體鈉/氫交換蛋白質2抗體
    • 產品貨號:
      BN41401R
    • 中文名稱:
      線粒體鈉/氫交換蛋白質2抗體
    • 英文名稱:
      Rabbit anti-NHEDC2 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41401R-100ul

      100ul

      ¥2360.00

      交叉反應:Human,Mouse(predicted:Rat,Dog,Rabbit) 推薦應用:WB,ELISA

    • BN41401R-200ul

      200ul

      ¥3490.00

      交叉反應:Human,Mouse(predicted:Rat,Dog,Rabbit) 推薦應用:WB,ELISA

    產品描述

    英文名稱NHEDC2
    中文名稱線粒體鈉/氫交換蛋白質2抗體
    別    名NHA2; Mitochondrial Na(+)/H(+) exchanger NHA2; Mitochondrial sodium/hydrogen exchanger NHA2; Na(+)/H(+) exchanger like domain containing protein 2; Na+/H+ exchanger domain containing 2; NHE domain containing protein 2; NHE10; NHEDC 2; Sodium/hydrogen exchanger like domain containing protein 2; SL9B2_HUMAN.  
    研究領域細胞生物  信號轉導  細胞周期蛋白  細胞分化  細胞骨架  細胞外基質  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse,  (predicted: Rat, Dog, Rabbit, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量58kDa
    細胞定位細胞漿 細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human NHEDC2:151-250/537 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events.

    Function:
    Electroneutral exchange of protons for Na(+) and Li(+)across the inner mitochondrial membrane. Contributes to theorganellar volume homeostasis. Required for osteoclastdifferentiation and bone resorption activity (By similarity).

    Subcellular Location:
    Mitochondrion membrane; Multi-pass membraneprotein (By similarity).

    Tissue Specificity:
    Detected in red blood cells (at proteinlevel).

    Similarity:
    Belongs to the monovalent cation:proton antiporter 1(CPA1) transporter (TC 2.A.36) family.

    SWISS:
    Q86UD5

    Gene ID:
    133308

    Database links:

    Entrez Gene: 133308 Human

    Entrez Gene: 97086 Mouse

    Entrez Gene: 365946 Rat

    Omim: 611789 Human

    SwissProt: Q86UD5 Human

    SwissProt: Q5BKR2 Mouse

    Unigene: 546482 Human

    Unigene: 441764 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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