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    首頁>>免疫學(xué)>>一抗>>核通道蛋白SEH1L抗體
    核通道蛋白SEH1L抗體
    • 產(chǎn)品貨號:
      BN41350R
    • 中文名稱:
      核通道蛋白SEH1L抗體
    • 英文名稱:
      Rabbit anti-SEH1L Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產(chǎn)品規(guī)格

      售價

      備注

    • BN41350R-100ul

      100ul

      ¥2360.00

      交叉反應(yīng):Rat(predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Rabbit) 推薦應(yīng)用:IHC-P,IHC-F,ICC,IF,ELISA

    • BN41350R-200ul

      200ul

      ¥3490.00

      交叉反應(yīng):Rat(predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Rabbit) 推薦應(yīng)用:IHC-P,IHC-F,ICC,IF,ELISA

    產(chǎn)品描述

    英文名稱SEH1L
    中文名稱核通道蛋白SEH1L抗體
    別    名Nucleoporin SEH1; Nup107-160 subcomplex subunit SEH1; SEC13-like protein; SEC13L; Seh 1; SEH1-like (S. cerevisiae); SEH1_HUMAN; SEH1A; SEH1B; SEH1L  
    研究領(lǐng)域細胞生物  免疫學(xué)  染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Rat,  (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Rabbit, )
    產(chǎn)品應(yīng)用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量40kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human SEH1L:1-100/360 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹Seh1 is a 421 amino acid protein belonging to the WD repeat Sec13 family. Localized to the nucleus, Seh1 is a component of the nuclear pore complex Nup107-160. Nuclear pore complexes control bidirectional transport of macromolecules between the cytoplasm and the nucleus. All components of the complex Nup107-160, including Seh1, localize to the kinetochores during mitosis. Seh1 is expressed as two isoforms produced by alternative splicing and contains six WD repeats.

    Function:
    Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.

    Subcellular Location:
    Chromosome; centromere; kinetochore. Nucleus; nuclear pore complex.

    Similarity:
    Belongs to the WD repeat SEC13 family.
    Contains 6 WD repeats.

    SWISS:
    Q96EE3

    Gene ID:
    81929

    Database links:

    Entrez Gene: 81929 Human

    Omim: 609263 Human

    SwissProt: Q96EE3 Human

    Unigene: 301048 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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