最近搜索:細胞培養 微生物學 分子生物 生物化學
    首頁>>免疫學>>一抗>>波形蛋白抗體
    波形蛋白抗體
    • 產品貨號:
      BN41335R
    • 中文名稱:
      波形蛋白抗體
    • 英文名稱:
      Rabbit anti-Vimentin Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41335R-100ul

      100ul

      ¥2360.00

      交叉反應:Rabbit,Mouse,Human(predicted:Horse,Cow,Pig,Dog,Rat) 推薦應用:WB,IHC-F,ICC,IF,Flow-Cyt,ELISA

    • BN41335R-200ul

      200ul

      ¥3490.00

      交叉反應:Rabbit,Mouse,Human(predicted:Horse,Cow,Pig,Dog,Rat) 推薦應用:WB,IHC-F,ICC,IF,Flow-Cyt,ELISA

    產品描述

    英文名稱Vimentin
    中文名稱波形蛋白抗體
    別    名VIM; FLJ36605; OTTHUMP00000019224; VIM; VIME_HUMAN; Vimentin. 
    研究領域腫瘤  細胞生物  免疫學  信號轉導  干細胞  細胞骨架  腫瘤細胞生物標志物  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse, Rabbit,  (predicted: Rat, Dog, Pig, Cow, Horse, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量51kDa
    細胞定位細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Vimentin:371-466/466 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009]

    Function:
    Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. Subunit : Homopolymer assembled from elementary dimers. Interacts with HCV core protein. Interacts with LGSN and SYNM. Interacts (via rod region) with PLEC (via CH 1 domain) (By similarity). Interacts with SLC6A4. Interacts with STK33. Interacts with LARP6. Interacts with RAB8B (By similarity).

    Subcellular Location:
    Cytoplasm.

    Tissue Specificity:
    Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.

    Post-translational modifications:
    Filament disassembly during mitosis is promoted by phosphorylation at Ser-55 as well as by nestin. One of the most prominent phosphoproteins in various cells of mesenchymal origin. Phosphorylation is enhanced during cell division, at which time vimentin filaments are significantly reorganized. Phosphorylation by PKN1 inhibits the formation of filaments. Phosphorylated at Ser-56 by CDK5 during neutrophil secretion in the cytoplasm. Phosphorylated by STK33.

    Similarity:
    Belongs to the intermediate filament family.

    SWISS:
    P08670

    Gene ID:
    7431

    Database links:

    Entrez Gene: 7431 Human

    Entrez Gene: 22352 Mouse

    Entrez Gene: 81818 Rat

    Omim: 193060 Human

    SwissProt: P08670 Human

    SwissProt: P20152 Mouse

    SwissProt: P31000 Rat

    Unigene: 455493 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


    久久精品国产69国产精品亚洲| 亚洲中文字幕丝袜制服一区| 亚洲ⅴ国产v天堂a无码二区| 国外亚洲成AV人片在线观看| 国产亚洲?V无码?V男人的天堂| 亚洲免费无码在线| 亚洲精品国产综合久久一线| www.91亚洲| 亚洲欧洲中文日韩久久AV乱码| 亚洲日韩中文字幕日韩在线| 亚洲国产精品一区二区第一页免| 亚洲精品国产精品国自产观看| 亚洲精品线路一在线观看| 久久精品国产精品亚洲| 不卡精品国产_亚洲人成在线| 在线观看国产区亚洲一区成人| 亚洲愉拍99热成人精品热久久| 亚洲一区无码中文字幕| 亚洲国产精品乱码一区二区 | 亚洲精品乱码久久久久久| 亚洲精品美女久久777777| 亚洲gv白嫩小受在线观看| 亚洲国产成人久久精品动漫| 久久精品国产亚洲AV大全| 亚洲国产av高清无码| 亚洲xxxx视频| 国产精品亚洲专一区二区三区| 亚洲国产精品毛片av不卡在线 | 国产亚洲AV手机在线观看| 亚洲成AV人片在线观看无码| 久久亚洲精品中文字幕无码| 亚洲美女视频网址| 日韩亚洲国产综合高清| 国产偷国产偷亚洲清高APP| 亚洲精品NV久久久久久久久久| 亚洲精品国产精品乱码在线观看| 亚洲AV成人无码久久精品老人| 亚洲女人18毛片水真多| 亚洲久悠悠色悠在线播放| 日韩亚洲翔田千里在线| 亚洲一区二区三区香蕉|