最近搜索:細胞培養 微生物學 分子生物 生物化學
    首頁>>免疫學>>一抗>>淋巴細胞性白血病相關序列1抗體
    淋巴細胞性白血病相關序列1抗體
    • 產品貨號:
      BN41316R
    • 中文名稱:
      淋巴細胞性白血病相關序列1抗體
    • 英文名稱:
      Rabbit anti-LYL1 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41316R-100ul

      100ul

      ¥2360.00

      交叉反應:Human(predicted:Mouse,Rat,Pig,Cow) 推薦應用:WB,Flow-Cyt,ELISA

    • BN41316R-200ul

      200ul

      ¥3490.00

      交叉反應:Human(predicted:Mouse,Rat,Pig,Cow) 推薦應用:WB,Flow-Cyt,ELISA

    產品描述

    英文名稱LYL1
    中文名稱淋巴細胞性白血病相關序列1抗體
    別    名Lyl1; Lymphoblastic leukemia derived sequence 1; Protein lyl 1.  
    研究領域腫瘤  細胞生物  免疫學  表觀遺傳學  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human,  (predicted: Mouse, Rat, Pig, Cow, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=1ug/test 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量31kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human LYL1:151-250/280 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹The Lyl1 gene encodes a basic helix–loop–helix transcription factor involved in T-cell acute lymphoblastic leukemia. The expression of Lyl1 is at higher levels in the majority of cases of acute myeloblastic leukemia (AML) or myelodysplastic syndrome when compared to normal bone marrow. Lyl1 is highly expressed in most AML cell lines.Lyl-1, TAL1 and TAL2 are part of a family of basic helix-loop-helix (bHLH) proteins implicated in T cell acute leukemia. TAL1, also designated SCL, is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. TAL2 is a protein involved in T cell acute lymphoblastic leukemia through a chromosomal translocation involving TAL2 and T cell receptor ∫ chain genes. TAL2 includes a helix-loop-helix protein dimerization and DNA-binding domain that is homologous to TAL1 and Lyl-1 proto-oncogenes. Lyl-1 (lymphoblastic leukemia-derived sequence 1) is a nuclear protein. Endogenous Lyl-1 exists in complex with E2? proteins. Lyl-1 and E2? protein can form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells. Lyl-1 is involved in a chromosomal aberration which causes a form of T cell acute lymphoblastic leukemia (T-ALL).

    Function:
    Efficient DNA binding requires dimerization with another bHLH protein.

    Subcellular Location:
    Nucleus (Potential).

    DISEASE:
    Note=A chromosomal aberration involving LYL1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(7;19)(q35;p13) with TCRB.

    Similarity:
    Contains 1 basic helix-loop-helix (bHLH) domain.

    SWISS:
    P12980

    Gene ID:
    4066

    Database links:

    Entrez Gene: 4066 Human

    Entrez Gene: 17095 Mouse

    Entrez Gene: 304663 Rat

    Omim: 151440 Human

    SwissProt: P12980 Human

    SwissProt: P27792 Mouse

    SwissProt: Q66HH3 Rat

    Unigene: 46446 Human

    Unigene: 728534 Human

    Unigene: 4925 Mouse

    Unigene: 17352 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.















    image.png

    亚洲αv在线精品糸列| 亚洲美日韩Av中文字幕无码久久久妻妇| 亚洲Aⅴ在线无码播放毛片一线天| 亚洲视频国产精品| 亚洲va国产va天堂va久久| 亚洲精品无码午夜福利中文字幕 | 日本亚洲成高清一区二区三区 | 亚洲AV无码专区在线电影成人 | www.亚洲成在线| 亚洲av永久无码精品三区在线4| 亚洲视频免费播放| 亚洲精品欧洲精品| 亚洲国产精品yw在线观看| 亚洲日韩中文字幕天堂不卡| 亚洲婷婷在线视频| 亚洲国产精品综合一区在线| 亚洲国产美女在线观看| 亚洲国产精品网站久久| 亚洲天堂男人影院| 亚洲欧美日韩中文无线码| 亚洲av色香蕉一区二区三区| 精品久久久久亚洲| 亚洲精品第一国产综合境外资源| 亚洲日韩在线观看免费视频| 国产午夜亚洲精品理论片不卡| 亚洲中文字幕无码久久2017| 国产亚洲精品无码成人| 亚洲人成网站在线播放影院在线| 久久国产亚洲高清观看| 亚洲91精品麻豆国产系列在线| 中文字幕在线观看亚洲日韩| 亚洲av日韩精品久久久久久a| 亚洲av高清在线观看一区二区| 久久久精品国产亚洲成人满18免费网站 | 亚洲女子高潮不断爆白浆| 国产精品无码亚洲精品2021| 亚洲午夜精品一级在线播放放| 国产亚洲3p无码一区二区| 夜夜亚洲天天久久| 亚洲六月丁香婷婷综合| 亚洲AV无码AV吞精久久|