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    細胞周期蛋白G相關激酶抗體
    • 產品貨號:
      BN41287R
    • 中文名稱:
      細胞周期蛋白G相關激酶抗體
    • 英文名稱:
      Rabbit anti-GAK protein Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41287R-100ul

      100ul

      ¥2360.00

      交叉反應:Mouse(predicted:Human,Rat,Chicken,Dog,Cow,Horse) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN41287R-200ul

      200ul

      ¥3490.00

      交叉反應:Mouse(predicted:Human,Rat,Chicken,Dog,Cow,Horse) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    產品描述

    英文名稱GAK protein
    中文名稱細胞周期蛋白G相關激酶抗體
    別    名Cyclin G associated kinase; Cyclin-G-associated kinase; EC 2.7.11.1; FLJ16629; FLJ40395; GAK; GAK protein; GAK_HUMAN; MGC99654.  
    研究領域細胞生物  神經生物學  信號轉導  細胞周期蛋白  激酶和磷酸酶  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Mouse,  (predicted: Human, Rat, Chicken, Dog, Cow, Horse, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量144kDa
    細胞定位細胞漿 細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human GAK protein:244-330/1311 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.
    Tissue specificity: Ubiquitous. Highest in testis.

    Function:
    Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.

    Subcellular Location:
    Cytoplasm, perinuclear region. Golgi apparatus, trans-Golgi network. Cell junction, focal adhesion (Probable). Note=Localizes to the perinuclear area and to the trans-Golgi network. Also seen on the plasma membrane, probably at focals adhesions.

    Tissue Specificity:
    Ubiquitous. Highest in testis.

    Similarity:
    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
    Contains 1 C2 tensin-type domain.
    Contains 1 J domain.
    Contains 1 phosphatase tensin-type domain.
    Contains 1 protein kinase domain.

    SWISS:
    O14976

    Gene ID:
    2580

    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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