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    Irx3蛋白抗體
    • 產品貨號:
      BN41280R
    • 中文名稱:
      Irx3蛋白抗體
    • 英文名稱:
      Rabbit anti-Iroquois homeobox protein 3 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41280R-100ul

      100ul

      ¥2360.00

      交叉反應:Mouse,Rat(predicted:Human,Dog,Pig,Cow) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN41280R-200ul

      200ul

      ¥3490.00

      交叉反應:Mouse,Rat(predicted:Human,Dog,Pig,Cow) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    產品描述

    英文名稱Iroquois homeobox protein 3
    中文名稱Irx3蛋白抗體
    別    名IRXB1; Homeodomain protein IRXB1; Iroquois homeobox protein 3; Iroquois-class homeodomain protein IRX-3; IRX 1; Irx3; IRX3_HUMAN; AI894186.  
    研究領域細胞生物  神經生物學  細胞周期蛋白  細胞分化  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量52kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Iroquois homeobox protein 3:401-501/501 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells.

    Function:
    Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity).

    Subunit:
    Belongs to the TALE/IRO homeobox family.
    Contains 1 homeobox DNA-binding domain.

    Subcellular Location:
    Nucleus.

    Similarity:
    Belongs to the TALE/IRO homeobox family.
    Contains 1 homeobox DNA-binding domain.

    SWISS:
    P78415

    Gene ID:
    79191

    Database links:
    UniProtKB/Swiss-Prot: P78415.3

    Entrez Gene: 79191 Human

    Entrez Gene: 16373 Mouse

    Omim: 612985 Human

    SwissProt: P78415 Human

    SwissProt: P81067 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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