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    首頁>>免疫學>>一抗>>絲氨酸/蘇氨酸蛋白激酶Nek7抗體
    絲氨酸/蘇氨酸蛋白激酶Nek7抗體
    • 產品貨號:
      BN41271R
    • 中文名稱:
      絲氨酸/蘇氨酸蛋白激酶Nek7抗體
    • 英文名稱:
      Rabbit anti-NEK7 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41271R-100ul

      100ul

      ¥2360.00

      交叉反應:Mouse,Rat(predicted:Human,Chicken,Pig,Cow,Rabbit,Sheep) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN41271R-200ul

      200ul

      ¥3490.00

      交叉反應:Mouse,Rat(predicted:Human,Chicken,Pig,Cow,Rabbit,Sheep) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    產品描述

    英文名稱NEK7
    中文名稱絲氨酸/蘇氨酸蛋白激酶Nek7抗體
    別    名NEK7; NEK7_HUMAN; Never in mitosis A-related kinase 7; Never in mitosis gene a-related kinase 7; NIMA (never in mitosis gene a) related kinase 7; NIMA (never in mitosis gene a)-related expressed kinase 7; NimA related protein kinase 7; NIMA-related kinase 7; NimA-related protein kinase 7; Serine/threonine-protein kinase Nek7.  
    研究領域細胞生物  信號轉導  激酶和磷酸酶  細胞分化  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Mouse, Rat,  (predicted: Human, Chicken, Pig, Cow, Rabbit, Sheep, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量35kDa
    細胞定位細胞核 細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human NEK7:101-200/302 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Tissue specificity: Highly expressed in lung, muscle, testis, brain, heart, liver, leukocyte and spleen. Lower expression in ovary, prostate and kidney.

    Function:
    Protein kinase which plays an important role in mitotic cell cycle progression. Required for microtubule nucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis. Phosphorylates RPS6KB1.

    Subunit:
    Monomer. Interacts with NEK9.

    Subcellular Location:
    Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, centrosome. Note=Present at centrosome throughout the cell cycle. Also detected at spindle midzone of the anaphase cells and eventually concentrates at the midbody.

    Tissue Specificity:
    Highly expressed in lung, muscle, testis, brain, heart, liver, leukocyte and spleen. Lower expression in ovary, prostate and kidney. No expression seen in small intestine.

    Post-translational modifications:
    Phosphorylation at Ser-195 required for its activation.

    Similarity:
    Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
    Contains 1 protein kinase domain.

    SWISS:
    Q8TDX7

    Gene ID:
    140609

    Database links:
    UniProtKB/Swiss-Prot: Q8TDX7.1

    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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