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    肌萎縮相關蛋白1抗體
    • 產品貨號:
      BN41245R
    • 中文名稱:
      肌萎縮相關蛋白1抗體
    • 英文名稱:
      Rabbit anti-RERE Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41245R-100ul

      100ul

      ¥2360.00

      交叉反應:Human,Mouse(predicted:Rat,Chicken,Dog,Cow,Horse) 推薦應用:IHC-P,IHC-F,IF,ELISA

    • BN41245R-200ul

      200ul

      ¥3490.00

      交叉反應:Human,Mouse(predicted:Rat,Chicken,Dog,Cow,Horse) 推薦應用:IHC-P,IHC-F,IF,ELISA

    產品描述

    英文名稱RERE
    中文名稱肌萎縮相關蛋白1抗體
    別    名ARG; arginine glutamic acid dipeptide (RE) repeats; arginine glutamic acid dipeptide repeats; Arginine glutamic acid dipeptide repeats protein; Arginine-glutamic acid dipeptide repeats protein; ARGININE-GLUTAMIC ACID REPEATS-ENCODING GENE; ARP; ATN1L; Atr2; atrophin 1 like; Atrophin 1 like protein; Atrophin 1 related protein; atrophin 2; atrophin related protein; ATROPHIN-1-ASSOCIATED PROTEIN; Atrophin-1-like protein; Atrophin-1-related protein; atrophin-2; ATROPHIN-RELATED PROTEIN; DNB1; Rere; RERE_HUMAN.  
    研究領域細胞生物  信號轉導  細胞凋亡  轉錄調節因子  表觀遺傳學  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse,  (predicted: Rat, Chicken, Dog, Cow, Horse, )
    產品應用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量172kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human RERE:521-620/1566 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹FunctionPlays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.

    Function:
    Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.

    Subunit:
    Interacts with HDAC1 (By similarity). Interacts with ATN1. Interaction with ATN1 is improved when the poly-Gln region of ATN1 is extended. Interacts with FAT1.

    Subcellular Location:
    Nucleus. Note=Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs.

    Tissue Specificity:
    Widely expressed. Expressed in tumor cell lines.

    DISEASE:
    Note=A chromosomal aberration involving RERE is found in the neuroblastoma cell line NGP. Translocation t(1;15)(p36.2;q24).

    Similarity:
    Contains 1 BAH domain.
    Contains 1 ELM2 domain.
    Contains 1 GATA-type zinc finger.
    Contains 1 SANT domain.

    SWISS:
    Q9P2R6

    Gene ID:
    473

    Database links:
    UniProtKB/Swiss-Prot: Q9P2R6.2

    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
















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