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    上游結(jié)合蛋白1抗體
    • 產(chǎn)品貨號(hào):
      BN41230R
    • 中文名稱(chēng):
      上游結(jié)合蛋白1抗體
    • 英文名稱(chēng):
      Rabbit anti-Upstream Binding Protein 1 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號(hào)

      產(chǎn)品規(guī)格

      售價(jià)

      備注

    • BN41230R-100ul

      100ul

      ¥2360.00

      交叉反應(yīng):Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse) 推薦應(yīng)用:WB,ELISA

    • BN41230R-200ul

      200ul

      ¥3490.00

      交叉反應(yīng):Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse) 推薦應(yīng)用:WB,ELISA

    產(chǎn)品描述

    英文名稱(chēng)Upstream Binding Protein 1
    中文名稱(chēng)上游結(jié)合蛋白1抗體
    別    名LBP 1a; Cp2b; DKFZp686L1745; LBP 1a; LBP 1B; LBP1; LBP1A; LBP1B; NF2d9; Upstream binding protein 1; Transcription factor LBP-1; UBIP1_HUMAN.  
    研究領(lǐng)域腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  表觀(guān)遺傳學(xué)  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應(yīng)Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量60kDa
    細(xì)胞定位細(xì)胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Upstream Binding Protein 1:351-450/540 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.

    Function:
    UBP1 is an important SF1 independent transcriptional activator stimulating P450scc expression in human placental JEG 3 cells.

    Subunit:
    Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1.

    Subcellular Location:
    Nucleus.

    Tissue Specificity:
    Expressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines.

    Similarity:
    Belongs to the grh/CP2 family. CP2 subfamily.

    SWISS:
    Q9NZI7

    Gene ID:
    7342

    Database links:

    Entrez Gene: 7342 Human

    Entrez Gene: 22221 Mouse

    Entrez Gene: 301038 Rat

    Omim: 609784 Human

    SwissProt: Q86Y57 Human

    SwissProt: Q9NZI7 Human

    SwissProt: Q60786 Mouse

    SwissProt: Q811S7 Mouse

    SwissProt: Q8BH21 Mouse

    Unigene: 118041 Human

    Unigene: 729120 Human

    Unigene: 28052 Mouse

    Unigene: 386808 Mouse

    Unigene: 15705 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.














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