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    睪丸酸性磷酸酶抗體
    • 產品貨號:
      BN41208R
    • 中文名稱:
      睪丸酸性磷酸酶抗體
    • 英文名稱:
      Rabbit anti-ACPT Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41208R-100ul

      100ul

      ¥2360.00

      交叉反應:Human(predicted:Mouse,Rat,Dog,Horse) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

    • BN41208R-200ul

      200ul

      ¥3490.00

      交叉反應:Human(predicted:Mouse,Rat,Dog,Horse) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

    產品描述

    英文名稱ACPT
    中文名稱睪丸酸性磷酸酶抗體
    別    名Acid phosphatase testicular; Testicular acid phosphatase; PPAT_HUMAN.  
    研究領域腫瘤  細胞生物  信號轉導  生長因子和激素  轉錄調節因子  腫瘤細胞生物標志物  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human,  (predicted: Mouse, Rat, Dog, Horse, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2ug/test IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量47kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human ACPT:65-160/437 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is upregulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. ACPT dephosphorylates receptor tyrosine-protein kinase erbB-4 and inhibits the ligand-induced proteolytic cleavage. ACPT is predominantly expressed in testis but exhibits a lower level of expression in testicular cancer tissues than in normal tissues. ACPT has structural similarity to prostatic and lysosomal acid phosphatases. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

    Subcellular Location:
    Membrane; Single-pass type II membrane protein (Potential).

    Tissue Specificity:
    High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract.

    Similarity:
    Belongs to the peptidase S1 family.
    Contains 1 LDL-receptor class A domain.
    Contains 1 peptidase S1 domain.
    Contains 1 SRCR domain.

    SWISS:
    Q9BZG2

    Gene ID:
    93650

    Database links:

    Entrez Gene: 93650 Human

    Omim: 606362 Human

    SwissProt: Q9BZG2 Human

    Unigene: 293394 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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