最近搜索:細胞培養 微生物學 分子生物 生物化學
    首頁>>免疫學>>一抗>>絲氨酸/蘇氨酸蛋白激酶38抗體
    絲氨酸/蘇氨酸蛋白激酶38抗體
    • 產品貨號:
      BN41205R
    • 中文名稱:
      絲氨酸/蘇氨酸蛋白激酶38抗體
    • 英文名稱:
      Rabbit anti-STK38 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41205R-100ul

      100ul

      ¥2360.00

      交叉反應:Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse,GuineaPig) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN41205R-200ul

      200ul

      ¥3490.00

      交叉反應:Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse,GuineaPig) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    產品描述

    英文名稱STK38
    中文名稱絲氨酸/蘇氨酸蛋白激酶38抗體
    別    名NDR 1; NDR1; NDR1 protein kinase; Nuclear Dbf2 related kinase 1; Serine/threonine protein kinase 38; STK 38; STK-38; STK38_HUMAN.  
    研究領域腫瘤  細胞生物  免疫學  信號轉導  激酶和磷酸酶  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse,  (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, Guinea Pig, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量51kDa
    細胞定位細胞核 細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human STK38:31-130/465 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹STK38 belongs to the NDR family of serine/threonine protein kinases. NDR kinases require the phosphorylation of conserved Ser/Thr residues for activation. NDR family members have two unique stretches of primary sequence: an N-terminal regulatory (NTR) domain and an insert of several residues between subdomains VII and VIII of the kinase domain. The kinase domain insert functions as an auto-inhibitory sequence (AIS), while binding of the co-activator MOB (Mps-one binder) proteins to the NTR domain releases NDR kinases from inhibition of autophosphorylation. STK38 negatively regulates the activation of MEKK1/2 by direct interaction with the catalytic domain of MEKK1/2. The negative regulation of MEKK1/2 is not due to its phosphorylation by STK38.

    Function:
    Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its nonphosphorylated form and inhibits autophosphorylation of MAP3K2.

    Subunit:
    Homodimeric S100B binds two molecules of STK38.

    Subcellular Location:
    Nucleus. Cytoplasm.

    Tissue Specificity:
    Ubiquitously expressed with highest levels observed in peripheral blood leukocytes.

    Post-translational modifications:
    ISGylated (Probable).
    Phosphorylated by STK3/MST2 and this is enhanced by MOBKL1B.

    Similarity:
    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. Contains 1 AGC-kinase C-terminal domain. Contains 1 protein kinase domain.

    SWISS:
    Q15208

    Gene ID:
    11329

    Database links:

    Entrez Gene: 11329 Human

    Entrez Gene: 106504 Mouse

    Omim: 606964 Human

    SwissProt: Q15208 Human

    SwissProt: Q91VJ4 Mouse

    Unigene: 409578 Human

    Unigene: 439986 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


















    image.png

    image.png

    亚洲午夜成人精品无码色欲| 亚洲大尺度无码专区尤物| 亚洲av伊人久久综合密臀性色| 亚洲情A成黄在线观看动漫软件 | 亚洲黄色在线视频| 亚洲v高清理论电影| 亚洲国产一区二区三区青草影视| 亚洲精品~无码抽插| 国产v亚洲v天堂无码网站| 久久精品国产亚洲网站| 亚洲国产精品无码久久SM| 亚洲处破女AV日韩精品| 亚洲福利在线视频| 亚洲美女视频免费| 亚洲伊人久久大香线蕉| 国产精品高清视亚洲精品| 亚洲中文无码永久免费| 亚洲欧洲AV无码专区| 亚洲国产午夜精品理论片在线播放| 亚洲精品美女久久7777777| 亚洲成av人片天堂网无码】| 无码天堂va亚洲va在线va| yy6080亚洲一级理论| 亚洲情a成黄在线观看| 国产偷国产偷亚洲清高动态图 | 香蕉大伊亚洲人在线观看| 亚洲精品国产精品国自产网站| 最新亚洲精品国偷自产在线| 亚洲区日韩精品中文字幕| 国产精品亚洲天堂| 久久久久亚洲精品无码网址 | 在线观看亚洲AV日韩AV| 亚洲а∨精品天堂在线| 亚洲国产一成久久精品国产成人综合 | 小说专区亚洲春色校园| 精品亚洲一区二区三区在线播放| 亚洲精品无码Av人在线观看国产| 久久久影院亚洲精品| 亚洲午夜一区二区电影院| 亚洲精品人成网线在线播放va| 亚洲国产一区二区视频网站|