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    α2纖溶酶色素上皮衍生因子抗體
    • 產品貨號:
      BN41196R
    • 中文名稱:
      α2纖溶酶色素上皮衍生因子抗體
    • 英文名稱:
      Rabbit anti-Alpha 2 antiplasmin Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41196R-100ul

      100ul

      ¥2360.00

      交叉反應:Human,Mouse,Rat(predicted:Dog,Horse,Rabbit) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN41196R-200ul

      200ul

      ¥3490.00

      交叉反應:Human,Mouse,Rat(predicted:Dog,Horse,Rabbit) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    產品描述

    英文名稱Alpha 2 antiplasmin
    中文名稱α2纖溶酶色素上皮衍生因子抗體
    別    名A2AP; A2AP_HUMAN; AAP; Alpha 2 antiplasmin; Alpha 2 antiplasmin pigment epithelium derived factor; Alpha 2 AP; ALPHA 2 PI; Alpha 2 plasmin inhibitor; Alpha 2 plasmin inhibitor deficiency; Alpha-2-antiplasmin; Alpha-2-AP; Alpha-2-PI; Alpha-2-plasmin inhibitor; Antiplasmin deficiency; API; Plasmin inhibitor deficiency; PLI; Serine (or cysteine) peptidase inhibitor, clade F, member 2; Serine (Or cysteine) peptidase inhibitor, clade F, member 2, isoform CRA_c; Serine (or cysteine) proteinase inhibitor, clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2; Serine (Or cysteine) proteinase inhibitor, clade F, member 2; Serine or cysteine peptidase inhibitor clade F member 2; Serpin F2; Serpin peptidase inhibitor clade F; Serpin peptidase inhibitor, clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2; SERPINF2.  






    研究領域心血管  細胞生物  免疫學  泛素  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse, Rat,  (predicted: Dog, Horse, Rabbit, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量50kDa
    細胞定位分泌型蛋白 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human SERPINF2:161-260/491 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Alpha 2 Antiplasmin is a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.

    Function:
    Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.

    Subunit:
    Forms protease inhibiting heterodimer with TMPRSS7.

    Subcellular Location:
    Secreted.

    Tissue Specificity:
    Expressed by the liver and secreted in plasma.

    DISEASE:
    Alpha-2-plasmin inhibitor deficiency (APLID) [MIM:262850]: An autosomal recessive disorder resulting in severe hemorrhagic diathesis. Note=The disease is caused by mutations affecting the gene represented in this entry.

    Similarity:
    Belongs to the serpin family.

    SWISS:
    P08697

    Gene ID:
    5345

    Database links:

    Entrez Gene: 5345 Human

    Omim: 613168 Human

    SwissProt: P08697 Human

    Unigene: 159509 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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