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Ras-GTP酶激活蛋白3抗體

產(chǎn)品貨號：

BN41181R
中文名稱：

Ras-GTP酶激活蛋白3抗體
英文名稱：

Rabbit anti-RASA3 Polyclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規(guī)格

售價

備注
BN41181R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse) 推薦應用：WB,ELISA
BN41181R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse) 推薦應用：WB,ELISA

產(chǎn)品描述

英文名稱	RASA3
中文名稱	Ras-GTP酶激活蛋白3抗體
別名	GAP III; GAP1(IP4BP); GAP1IP4BP; GAPIII; GTPase activating protein III; Inositol 1 3 4 5 tetrakisphosphate binding protein; Inositol 1345 tetrakisphosphate binding protein; Ins P4 binding protein; Ins(1 3 4 5)P4 binding protein; Ins(1345)P4 binding protein; Ras GTPase activating protein 3; RAS p21 protein activator 3; RASA 3.RASA3_HUMAN
研究領域	免疫學信號轉導 G蛋白偶聯(lián)受體
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse, (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, )
產(chǎn)品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	91kDa
細胞定位	細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human RASA3:501-600/834
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	RASA3 is a inhibitory regulator of the Ras-cyclic AMP pathway and is a member of the GAP1 family of GTPase-activating proteins. It stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. RASA3 is an inositol 1,3,4,5-tetrakisphosphate-binding protein (IP4). Function: Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor. Subcellular Location: Cell membrane. Similarity: Contains 1 Btk-type zinc finger. Contains 2 C2 domains. Contains 1 PH domain. Contains 1 Ras-GAP domain. SWISS: Q14644 Gene ID: 22821 Database links: Entrez Gene: 22821 Human Entrez Gene: 19414 Mouse Entrez Gene: 29372 Rat Omim: 605182 Human SwissProt: Q14644 Human SwissProt: Q60790 Mouse SwissProt: Q9QYJ2 Rat Unigene: 593075 Human Unigene: 18517 Mouse Unigene: 224604 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.