最近搜索:細胞培養 微生物學 分子生物 生物化學
    首頁>>免疫學>>一抗>>泛素特異性蛋白酶28抗體
    泛素特異性蛋白酶28抗體
    • 產品貨號:
      BN41171R
    • 中文名稱:
      泛素特異性蛋白酶28抗體
    • 英文名稱:
      Rabbit anti-USP28 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41171R-100ul

      100ul

      ¥2360.00

      交叉反應:Mouse(predicted:Human,Rat) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN41171R-200ul

      200ul

      ¥3490.00

      交叉反應:Mouse(predicted:Human,Rat) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    產品描述

    英文名稱USP28
    中文名稱泛素特異性蛋白酶28抗體
    別    名Deubiquitinating enzyme 28; KIAA1515; Ubiquitin carboxyl terminal hydrolase 28; Ubiquitin carboxyl-terminal hydrolase 28; Ubiquitin specific peptidase 28; Ubiquitin specific processing protease 28; Ubiquitin specific protease 28; Ubiquitin thioesterase 28; Ubiquitin thiolesterase 28; Ubiquitin-specific-processing protease 28; UBP28_HUMAN; USP 28; USP28; USP28 protein.  
    研究領域腫瘤  細胞生物  免疫學  染色質和核信號  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Mouse,  (predicted: Human, Rat, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量75/100kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human USP28:101-200/1077 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Deubiquitinase involved in DNA damage response checkpoint and MYC proto-oncogene stability. Involved in DNA damage induced apoptosis by specifically deubiquitinating proteins of the DNA damage pathway such as CLSPN. Also involved in G2 DNA damage checkpoint, by deubiquitinating CLSPN, and preventing its degradation by the anaphase promoting complex/cyclosome (APC/C). In contrast, it does not deubiquitinate PLK1. Specifically deubiquitinates MYC in the nucleoplasm, leading to prevent MYC degradation by the proteasome: acts by specifically interacting with isoform 1 of FBXW7 (FBW7alpha) in the nucleoplasm and counteracting ubiquitination of MYC by the SCF(FBW7) complex. In contrast, it does not interact with isoform 4 of FBXW7 (FBW7gamma) in the nucleolus, allowing MYC degradation and explaining the selective MYC degradation in the nucleolus.

    SWISS:
    Q96RU2

    Gene ID:
    57646

    Database links:

    Entrez Gene: 57646 Human

    Entrez Gene: 235323 Mouse

    Entrez Gene: 315639 Rat

    Omim: 610748 Human

    SwissProt: Q96RU2 Human

    SwissProt: Q5I043 Mouse

    SwissProt: D3ZJ96 Rat

    Unigene: 503891 Human

    Unigene: 21630 Mouse

    Unigene: 6599 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


    亚洲综合色一区二区三区| 亚洲AV无码久久精品成人| 久久亚洲国产伦理| 国产亚洲精久久久久久无码77777| 久久精品国产亚洲AV天海翼| 亚洲夂夂婷婷色拍WW47| 亚洲国产一区在线观看| 亚洲欧洲精品视频在线观看| 久久久无码精品亚洲日韩按摩| 亚洲AV成人无码久久精品老人| 亚洲av永久无码精品漫画| 亚洲AV无码一区二区三区DV| 亚洲国产精品无码久久久蜜芽| 亚洲精品成人网站在线观看| 亚洲人成网站影音先锋播放| 亚洲色欲一区二区三区在线观看| 亚洲精品无码午夜福利中文字幕| 亚洲色欲久久久综合网| 久久99国产亚洲高清观看首页| 亚洲国产精品无码久久久秋霞2| 亚洲人成无码网站| 亚洲短视频男人的影院| 久久久亚洲AV波多野结衣| 亚洲国产精品午夜电影| 亚洲an日韩专区在线| 中文无码亚洲精品字幕| 亚洲AV永久无码精品一福利 | 亚洲AV乱码一区二区三区林ゆな| 亚洲国产成人一区二区三区| 久久久无码精品亚洲日韩蜜桃 | 亚洲精品免费观看| 亚洲的天堂av无码| 2020久久精品亚洲热综合一本| 在线精品亚洲一区二区| 国产成人精品久久亚洲高清不卡| 亚洲国产精品尤物YW在线观看| 亚洲人成色7777在线观看| 亚洲国产高清视频| 国产色在线|亚洲| 久久久久久久久无码精品亚洲日韩| 亚洲区小说区图片区|