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    磷酸甲羥戊酸激酶抗體
    • 產品貨號:
      BN41084R
    • 中文名稱:
      磷酸甲羥戊酸激酶抗體
    • 英文名稱:
      Rabbit anti-PMVK Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41084R-100ul

      100ul

      ¥2360.00

      交叉反應:Human,Mouse(predicted:Rat,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN41084R-200ul

      200ul

      ¥3490.00

      交叉反應:Human,Mouse(predicted:Rat,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    產品描述

    英文名稱PMVK
    中文名稱磷酸甲羥戊酸激酶抗體
    別    名hPMK; HUMPMKI; Phosphomevalonate kinase; PMK; PMK PEN; PMKA; PMKase; PMKI; PMKPEN; PMVK; PMVK_HUMAN; EC 2.7.4.2.  
    研究領域腫瘤  細胞生物  免疫學  信號轉導  轉錄調節因子  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse,  (predicted: Rat, Pig, Cow, Horse, Rabbit, Sheep, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量22kDa
    細胞定位細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated Synthesised phosphopeptide derived from human PMVK:15-120/192 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹PMVK is a 192 amino acid peroxisomal enzyme belonging to the nucleoside monophosphate (NMP) kinase family and is expressed in heart, liver, skeletal muscle, kidney, and pancreas with lower expression in brain, placenta and lung. Induced by sterol, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway. PMVK exists as a monomer and is encoded by a gene located on human chromosome 1, which houses over 3,000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.

    Subunit:
    Monomer (By similarity).

    Subcellular Location:
    Peroxisome.

    Tissue Specificity:
    Heart, liver, skeletal muscle, kidney, and pancreas. Lower level in brain, placenta and lung.

    SWISS:
    Q15126

    Gene ID:
    10654

    Database links:

    Entrez Gene: 10654 Human

    Entrez Gene: 68603 Mouse

    Entrez Gene: 310645 Rat

    Omim: 607622 Human

    SwissProt: Q15126 Human

    SwissProt: Q9D1G2 Mouse

    SwissProt: Q5RK24 Rat

    Unigene: 30954 Human

    Unigene: 34242 Mouse

    Unigene: 22202 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.











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