色噜噜国产在线91蝌蚪,a级毛片免费观看视频,欧美一级专区免费大片俄罗斯

<abbr id="e8yyq"></abbr>

<tfoot id="e8yyq"></tfoot>

Ki67蛋白抗體

產品貨號：

BN40754R
中文名稱：

Ki67蛋白抗體
英文名稱：

Rabbit anti-Ki-67 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN40754R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse 推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
BN40754R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse 推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

產品描述

英文名稱	Ki-67
中文名稱	Ki67蛋白抗體
別名	Antigen identified by monoclonal antibody Ki 67; Antigen KI67; KIA; Ki67; MKI67; Proliferation related Ki 67 antigen; Antigen KI-67; KI67_MOUSE.

研究領域	腫瘤細胞生物神經生物學細胞周期蛋白細胞分化細胞類型標志物表觀遺傳學
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse,
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	358kDa
細胞定位	細胞核
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from mouse Ki-67:1231-1330/2938
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation. Function: Thought to be required for maintaining cell proliferation. Subcellular Location: Nucleus. Chromosome. Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes. Similarity: Contains 1 FHA domain. SWISS: Q91VE6 Gene ID: 17345 Database links: Entrez Gene: 4288 Human Entrez Gene: 17345 Mouse Entrez Gene: 246042 Rat Omim: 176741 Human SwissProt: P46013 Human SwissProt: Q91VE6 Mouse SwissProt: Q5RJM0 Rat Unigene: 689823 Human Unigene: 80976 Human Unigene: 4078 Mouse Unigene: 233802 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 細胞增殖標志物(Proliferation Marker) Ki67與PCNA一樣，為細胞增殖的一種標記，在細胞凋亡中S、G2 、M期均有表達，G0期缺如。 Ki-67增殖指數高低與許多腫瘤的分化程度、浸潤、轉移以及預后密切相關，因此被廣泛作為各種惡性腫瘤的必檢項目之一。