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    驅(qū)動蛋白家族成員13A抗體
    • 產(chǎn)品貨號:
      BN40481R
    • 中文名稱:
      驅(qū)動蛋白家族成員13A抗體
    • 英文名稱:
      Rabbit anti-KIF13A Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產(chǎn)品規(guī)格

      售價

      備注

    • BN40481R-100ul

      100ul

      ¥2360.00

      交叉反應(yīng):Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應(yīng)用:IHC-P,IHC-F,ICC,IF,ELISA

    • BN40481R-200ul

      200ul

      ¥3490.00

      交叉反應(yīng):Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應(yīng)用:IHC-P,IHC-F,ICC,IF,ELISA

    產(chǎn)品描述

    英文名稱KIF13A
    中文名稱驅(qū)動蛋白家族成員13A抗體
    別    名bA500C11.2; FLJ27232; KI13A_HUMAN; KIF 13A; Kif13a; Kinesin family member 13A; Kinesin like protein KIF13A; Kinesin like protein RBKIN; Kinesin-like protein KIF13A; Kinesin-like protein RBKIN; RBKIN.  
    研究領(lǐng)域細(xì)胞生物  免疫學(xué)  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
    產(chǎn)品應(yīng)用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量202kDa
    細(xì)胞定位細(xì)胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human KIF13A:1501-1600/1805 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]

    Function:
    Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis.

    Subcellular Location:
    Cytoplasm > cytoskeleton > centrosome. Midbody. Endosome membrane. Golgi apparatus membrane. Recruited to the midbody during cytokinesis.

    Tissue Specificity:
    Widely expressed, with highest levels in heart, brain and skeletal muscle.

    Similarity:
    Belongs to the kinesin-like protein family.
    Contains 1 FHA domain.
    Contains 1 kinesin-motor domain.

    SWISS:
    Q9H1H9

    Gene ID:
    63971

    Database links:

    Entrez Gene: 63971 Human

    Omim: 605433 Human

    SwissProt: Q9H1H9 Human

    Unigene: 94499 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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