最近搜索:細胞培養 微生物學 分子生物 生物化學
    首頁>>免疫學>>一抗>>干擾素調節因子2抗體
    干擾素調節因子2抗體
    • 產品貨號:
      BN40480R
    • 中文名稱:
      干擾素調節因子2抗體
    • 英文名稱:
      Rabbit anti-IRF2 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN40480R-100ul

      100ul

      ¥2360.00

      交叉反應:Human,Mouse,Rat(predicted:Pig,Cow,Horse,Sheep) 推薦應用:IHC-P,IHC-F,ICC,IF,ELISA

    • BN40480R-200ul

      200ul

      ¥3490.00

      交叉反應:Human,Mouse,Rat(predicted:Pig,Cow,Horse,Sheep) 推薦應用:IHC-P,IHC-F,ICC,IF,ELISA

    產品描述

    英文名稱IRF2
    中文名稱干擾素調節因子2抗體
    別    名DKFZp686F0244; Interferon regulatory factor 2; IRF 2; IRF-2; IRF2; IRF2_HUMAN.  
    研究領域細胞生物  轉錄調節因子  表觀遺傳學  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse, Rat,  (predicted: Pig, Cow, Horse, Sheep, )
    產品應用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量39kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human IRF2:81-180/349 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. [provided by RefSeq, Jul 2008]

    Function:
    Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.

    Subcellular Location:
    Nucleus.

    Tissue Specificity:
    Expressed throughout the epithelium of the colon. Also expressed in lamina propria.

    Post-translational modifications:
    Acetylated by CBP/ p300 during cell-growth. Acetylation on Lys-75 is required for stimulation of H4 promoter activity.
    The major sites of sumoylation are Lys-137 and Lys-293. Sumoylation by SUMO1 increases its transcriptional repressor activity on IRF1 and diminishes its ability to activate ISRE and H4 promoter.

    Similarity:
    Belongs to the IRF family.
    Contains 1 IRF tryptophan pentad repeat DNA-binding domain.

    SWISS:
    P14316

    Gene ID:
    3660

    Database links:

    Entrez Gene: 3660 Human

    Entrez Gene: 16363 Mouse

    Omim: 147576 Human

    SwissProt: P14316 Human

    SwissProt: P23906 Mouse

    Unigene: 654566 Human

    Unigene: 1149 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.















    image.png

    image.png

    image.png

    image.png

    image.png

    image.png

    image.png

    image.png

    image.png

    亚洲中文字幕无码永久在线| 亚洲国产成人久久三区| 国产成人亚洲精品| 亚洲国产美女在线观看| 亚洲网址在线观看| 亚洲国产成人精品电影| 亚洲午夜久久久久久尤物| 亚洲精品福利网泷泽萝拉| 亚洲日韩乱码久久久久久| 亚洲妓女综合网99| 亚洲同性男gay网站在线观看| 亚洲日韩国产精品无码av| 亚洲丝袜中文字幕| 国产成人亚洲精品| 亚洲精品久久无码| 久久亚洲精品11p| 亚洲国产精品日韩| 国产亚洲情侣一区二区无| 亚洲另类激情综合偷自拍图| 亚洲va中文字幕无码久久不卡| 亚洲第一福利网站| 亚洲春色在线观看| 亚洲日日做天天做日日谢| 亚洲av最新在线观看网址| 91亚洲一区二区在线观看不卡| 亚洲AV日韩精品一区二区三区 | 亚洲网红精品大秀在线观看| 亚洲综合精品一二三区在线| 亚洲精品午夜在线观看| 亚洲jizzjizz在线播放久| 亚洲日韩AV一区二区三区中文| 久久精品亚洲日本波多野结衣| 国产亚洲福利精品一区二区 | 亚洲欧洲国产经精品香蕉网| 久久亚洲精品国产精品婷婷| 久久久久亚洲精品无码网址色欲| 亚洲美日韩Av中文字幕无码久久久妻妇| 狠狠亚洲狠狠欧洲2019| 亚洲av无码一区二区乱子伦as | www国产亚洲精品久久久日本| 国产精品亚洲不卡一区二区三区|