最近搜索:細(xì)胞培養(yǎng) 微生物學(xué) 分子生物 生物化學(xué)
    首頁>>免疫學(xué)>>一抗>>磷酸化微管相關(guān)蛋白2(Thr1613/1619)抗體
    磷酸化微管相關(guān)蛋白2(Thr1613/1619)抗體
    • 產(chǎn)品貨號(hào):
      BN40469R
    • 中文名稱:
      磷酸化微管相關(guān)蛋白2(Thr1613/1619)抗體
    • 英文名稱:
      Rabbit anti-Phospho-MAP2 (Thr1613/1619) Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號(hào)

      產(chǎn)品規(guī)格

      售價(jià)

      備注

    • BN40469R-100ul

      100ul

      ¥2470.00

      交叉反應(yīng):Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) 推薦應(yīng)用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

    產(chǎn)品描述

    英文名稱Phospho-MAP2 (Thr1613/1619)
    中文名稱磷酸化微管相關(guān)蛋白2(Thr1613/1619)抗體
    別    名MAP2(Phospho Thr1613/1619); MAP2 (phospho Thr1613/1619); p-MAP2 (phospho Thr1613/1619); MAP2(Phospho Thr1613/1619); MAP2(Phospho-Thr1613/1619); p-MAP2(Phospho-Thr1613/1619); DKFZp686I2148; Dendrite specific MAP; DKFZp686I2148; MAP 2; MAP-2; MAP2; MAP2_HUMAN; MAP2A; MAP2B; MAP2C; Microtubule associated protein 2; Microtubule-associated protein 2; Mtap 2.  
    產(chǎn)品類型磷酸化抗體 
    研究領(lǐng)域免疫學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  細(xì)胞凋亡  G蛋白信號(hào)  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量70/201kDa
    細(xì)胞定位細(xì)胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthesised phosphopeptide derived from human MAP2 around the phosphorylation site of Thr1613 and Thr1619:SR(p-T)PGTPG(p-T)PS 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.

    Function:
    The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

    Subcellular Location:
    Cytoplasm, cytoskeleton (Probable).

    Post-translational modifications:
    Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly. MAP2A/c is phosphorylated. Isoform MAP2c is phosphorylated by FYN at Tyr-67.

    Similarity:
    Contains 3 Tau/MAP repeats.

    SWISS:
    P11137

    Gene ID:
    4133

    Database links:

    Entrez Gene: 4133 Human

    Entrez Gene: 17756 Mouse

    Entrez Gene: 25595 Rat

    Omim: 157130 Human

    SwissProt: P11137 Human

    SwissProt: P20357 Mouse

    SwissProt: P15146 Rat

    Unigene: 368281 Human

    Unigene: 256966 Mouse

    Unigene: 10484 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


    国产亚洲无线码一区二区| 国产AV无码专区亚洲AV麻豆丫| 亚洲成在人线在线播放无码| 亚洲一区在线观看视频| 国产天堂亚洲精品| 亚洲6080yy久久无码产自国产 | 久久久久亚洲精品无码蜜桃| 亚洲欧洲精品国产区| 亚洲av无码专区亚洲av不卡| 67pao强力打造67194在线午夜亚洲| 亚洲国产综合人成综合网站00| 亚洲成a人片在线观看日本麻豆| 亚洲精品视频免费观看| 亚洲视频免费播放| 亚洲人成影院在线| 337P日本欧洲亚洲大胆艺术图 | 亚洲一区中文字幕在线电影网| 亚洲特级aaaaaa毛片| 无码乱人伦一区二区亚洲一| 在线免费观看亚洲| 色婷婷亚洲十月十月色天| 亚洲精品国产suv一区88| 久久精品国产亚洲av麻豆色欲 | 色天使色婷婷在线影院亚洲| 亚洲精品无码不卡在线播放HE| 亚洲va久久久噜噜噜久久狠狠| 精品亚洲综合在线第一区| 最新精品亚洲成a人在线观看| 久久精品国产亚洲av麻| 久久精品国产亚洲AV网站| 久久亚洲成a人片| 亚洲A∨精品一区二区三区下载| 国外亚洲成AV人片在线观看 | 亚洲中文字幕无码一去台湾 | 亚洲女人影院想要爱| 亚洲成a人片在线观看中文app| 亚洲一级片在线播放| 亚洲午夜成人精品无码色欲| 亚洲精品电影在线| 亚洲精品第一国产综合精品99| 亚洲人成在线影院|