最近搜索:細(xì)胞培養(yǎng) 微生物學(xué) 分子生物 生物化學(xué)
    首頁>>免疫學(xué)>>一抗>>磷酸化微管相關(guān)蛋白2(Thr1613/1619)抗體
    磷酸化微管相關(guān)蛋白2(Thr1613/1619)抗體
    • 產(chǎn)品貨號(hào):
      BN40469R
    • 中文名稱:
      磷酸化微管相關(guān)蛋白2(Thr1613/1619)抗體
    • 英文名稱:
      Rabbit anti-Phospho-MAP2 (Thr1613/1619) Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號(hào)

      產(chǎn)品規(guī)格

      售價(jià)

      備注

    • BN40469R-100ul

      100ul

      ¥2470.00

      交叉反應(yīng):Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) 推薦應(yīng)用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

    產(chǎn)品描述

    英文名稱Phospho-MAP2 (Thr1613/1619)
    中文名稱磷酸化微管相關(guān)蛋白2(Thr1613/1619)抗體
    別    名MAP2(Phospho Thr1613/1619); MAP2 (phospho Thr1613/1619); p-MAP2 (phospho Thr1613/1619); MAP2(Phospho Thr1613/1619); MAP2(Phospho-Thr1613/1619); p-MAP2(Phospho-Thr1613/1619); DKFZp686I2148; Dendrite specific MAP; DKFZp686I2148; MAP 2; MAP-2; MAP2; MAP2_HUMAN; MAP2A; MAP2B; MAP2C; Microtubule associated protein 2; Microtubule-associated protein 2; Mtap 2.  
    產(chǎn)品類型磷酸化抗體 
    研究領(lǐng)域免疫學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  細(xì)胞凋亡  G蛋白信號(hào)  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量70/201kDa
    細(xì)胞定位細(xì)胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthesised phosphopeptide derived from human MAP2 around the phosphorylation site of Thr1613 and Thr1619:SR(p-T)PGTPG(p-T)PS 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.

    Function:
    The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

    Subcellular Location:
    Cytoplasm, cytoskeleton (Probable).

    Post-translational modifications:
    Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly. MAP2A/c is phosphorylated. Isoform MAP2c is phosphorylated by FYN at Tyr-67.

    Similarity:
    Contains 3 Tau/MAP repeats.

    SWISS:
    P11137

    Gene ID:
    4133

    Database links:

    Entrez Gene: 4133 Human

    Entrez Gene: 17756 Mouse

    Entrez Gene: 25595 Rat

    Omim: 157130 Human

    SwissProt: P11137 Human

    SwissProt: P20357 Mouse

    SwissProt: P15146 Rat

    Unigene: 368281 Human

    Unigene: 256966 Mouse

    Unigene: 10484 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


    亚洲AV综合色区无码另类小说 | 亚洲欧洲一区二区三区| 亚洲美女视频一区二区三区| 亚洲AV无码久久精品成人| 亚洲国产精品不卡毛片a在线| 免费在线观看亚洲| 亚洲aⅴ无码专区在线观看春色| 亚洲成AV人影片在线观看| 亚洲成aⅴ人片久青草影院按摩| 亚洲日本VA中文字幕久久道具| 亚洲熟女精品中文字幕| 亚洲欧洲AV无码专区| 亚洲A∨精品一区二区三区下载| 亚洲av无码兔费综合| 国产亚洲视频在线观看网址| 亚洲 自拍 另类小说综合图区 | 亚洲变态另类一区二区三区| 亚洲精品无AMM毛片| 亚洲av无码一区二区三区人妖| 日日摸日日碰夜夜爽亚洲| 亚洲国产香蕉人人爽成AV片久久| 国产亚洲?V无码?V男人的天堂| 亚洲日韩精品射精日| 久久久久亚洲av无码尤物| 亚洲日本一区二区三区| 亚洲毛片一级带毛片基地| 亚洲天堂一区在线| 亚洲精品色播一区二区| 亚洲成?v人片天堂网无码| 不卡精品国产_亚洲人成在线| 自拍偷自拍亚洲精品情侣| 久久精品国产精品亚洲艾草网| 久久亚洲AV无码精品色午夜| 亚洲一区中文字幕| 亚洲a无码综合a国产av中文| 亚洲欧洲精品成人久久奇米网| 亚洲精品少妇30p| 亚洲色图视频在线观看| 亚洲永久在线观看| www.亚洲精品.com| 国产亚洲精品岁国产微拍精品|