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    細胞色素B5還原酶4抗體
    • 產品貨號:
      BN40442R
    • 中文名稱:
      細胞色素B5還原酶4抗體
    • 英文名稱:
      Rabbit anti-CYB5R4 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN40442R-100ul

      100ul

      ¥2360.00

      交叉反應:Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) 推薦應用:WB,IHC-P,IHC-F,ICC,IF,ELISA

    • BN40442R-200ul

      200ul

      ¥3490.00

      交叉反應:Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) 推薦應用:WB,IHC-P,IHC-F,ICC,IF,ELISA

    產品描述

    英文名稱CYB5R4
    中文名稱細胞色素B5還原酶4抗體
    別    名b5+b5R; b5b5r; C79736; cb5/cb5R; Cb5cb5r; Cyb5r4; Cytochrome b type NAD(P)H oxidoreductase; Cytochrome b5 reductase 4; dJ676J13.1; Flavohemoprotein b5+b5R; Flavohemoprotein b5/b5R; N terminal cytochrome b5 and cytochrome b5 oxidoreductase domain containing protein; N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein; NADPH cytochrome B5 oxidoreductase; NB5R4_HUMAN; NCB5OR; RP4 676J13.1.  
    研究領域細胞生物  神經生物學  細胞類型標志物  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Sheep, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量59kDa
    細胞定位細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human CYB5R4:21-120/521 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹NCB5OR is a flavohemoprotein that contains functional domains found in both cytochrome b5 (CYB5A; MIM 613218) and CYB5 reductase (CYB5R3; MIM 613213) (Zhu et al., 1999 [PubMed 10611283]).[supplied by OMIM, Jan 2010]

    Function:
    NADH-cytochrome b5 reductase involved in endolasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin.

    Subcellular Location:
    Endoplasmic reticulum. Soluble protein.

    Tissue Specificity:
    Widely expressed.

    Similarity:
    Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
    Contains 1 CS domain.
    Contains 1 cytochrome b5 heme-binding domain.
    Contains 1 FAD-binding FR-type domain.

    SWISS:
    Q7L1T6

    Gene ID:
    51167

    Database links:

    Entrez Gene: 51167 Human

    Omim: 608343 Human

    SwissProt: Q7L1T6 Human

    Unigene: 5741 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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