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轉錄因子SOX7抗體

產品貨號：

BN40359R
中文名稱：

轉錄因子SOX7抗體
英文名稱：

Rabbit anti-SOX7 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN40359R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse(predicted:Rat,Dog,Pig,Cow,Rabbit) 推薦應用：IHC-P,IHC-F,ICC,IF,ELISA
BN40359R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse(predicted:Rat,Dog,Pig,Cow,Rabbit) 推薦應用：IHC-P,IHC-F,ICC,IF,ELISA

產品描述

英文名稱	SOX7
中文名稱	轉錄因子SOX7抗體
別名	MGC10895; SOX 7; SOX 7 transcription factor; sox7; SOX7 transcription factor; SOX7_HUMAN; SRY (sex determining region Y) box 7; SRY box 7; SRY sex determining region Y box 7; Transcription factor SOX 7; Transcription factor Sox-7; Transcription factor SOX7.
研究領域	細胞生物發育生物學干細胞轉錄調節因子表觀遺傳學
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse, (predicted: Rat, Dog, Pig, Cow, Rabbit, )
產品應用	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	42kDa
細胞定位	細胞核
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human SOX7:42-100/388
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Function: Transcriptional repressor. Binds to the DNA sequence 5'-AACAAT-3'. Subunit: Interacts with CTNNB1/beta-catenin; this interaction may lead to the proteasomal degradation of active CTNNB1 and thus inhibition of Wnt/beta-catenin-stimulated transcription. Subcellular Location: Nucleus. Tissue Specificity: Widely expressed in adult and fetal tissues. Present both in mesenchymal and epithelial cells in some adult tissues, including colon. Tends to be down-regulated in prostate adenocarcinomas and colorectal tumors due to promoter hypermethylation. Similarity: Contains 1 HMG box DNA-binding domain. Contains 1 Sox C-terminal domain. SWISS: Q9BT81 Gene ID: 83595 Database links: Entrez Gene: 83595 Human Entrez Gene: 20680 Mouse Entrez Gene: 290317 Rat Entrez Gene: 378665 Xenopus laevis Omim: 612202 Human SwissProt: Q9BT81 Human SwissProt: P40646 Mouse SwissProt: O42342 Xenopus laevis Unigene: 709543 Human Unigene: 42162 Mouse Unigene: 1241 Xenopus laevis Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.