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    神經組織特異性F肌動蛋白結合蛋白抗體
    • 產品貨號:
      BN40342R
    • 中文名稱:
      神經組織特異性F肌動蛋白結合蛋白抗體
    • 英文名稱:
      Rabbit anti-Neurabin 1 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN40342R-100ul

      100ul

      ¥2360.00

      交叉反應:Mouse,Rat(predicted:Human,Dog,Pig,Cow,Rabbit,Sheep) 推薦應用:IHC-P,IHC-F,ICC,IF,ELISA

    • BN40342R-200ul

      200ul

      ¥3490.00

      交叉反應:Mouse,Rat(predicted:Human,Dog,Pig,Cow,Rabbit,Sheep) 推薦應用:IHC-P,IHC-F,ICC,IF,ELISA

    產品描述

    英文名稱Neurabin 1
    中文名稱神經組織特異性F肌動蛋白結合蛋白抗體
    別    名FLJ20068; KIAA1222; NEB1_HUMAN; Neurabin I; Neurabin-1; Neurabin-I; Neurabin1; Neurabin-1; NeurabinI; Neurabin1; Neural tissue specific F actin binding protein I; Neural tissue-specific F-actin-binding protein I; NRB 1; NRB I; NRB1; NRBI; PPP1R9A; Protein phosphatase 1 regulatory (inhibitor) subunit 9A; Protein phosphatase 1 regulatory subunit 9A.  
    研究領域細胞生物  神經生物學  轉運蛋白  細胞骨架  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Rabbit, Sheep, )
    產品應用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量123kDa
    細胞定位細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Neurabin 1/PPP1R9A:115-165/1098 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

    Function:
    Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity.

    Subcellular Location:
    Cytoplasm.

    Similarity:
    Contains 1 PDZ (DHR) domain.
    Contains 1 SAM (sterile alpha motif) domain.

    SWISS:
    Q9ULJ8

    Gene ID:
    55607

    Database links:

    Entrez Gene: 55607 Human

    Entrez Gene: 243725 Mouse

    Entrez Gene: 84685 Rat

    Omim: 602468 Human

    SwissProt: Q9ULJ8 Human

    SwissProt: O35867 Rat

    Unigene: 21816 Human

    Unigene: 10849 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.











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